SEMA3E

  • Official Full Name

    sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E

  • Overview

    Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.

  • Synonyms

    SEMA3E;sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E;SEMAH;semaphorin-3E;coll 5;KIAA0331;M sema H;M SemaK;coll-5;M-SEMAH;M-SemaK

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Chicken
  • E.coli
  • Mammalian cells
  • Mammalian Cell
  • HEK293
  • His
  • His&T7
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
SEMA3E-2574H Recombinant Human SEMA3E, His-tagged E.coli Human His C-211aa
SEMA3E-932H Active Recombinant Human SEMA3E Protein, His-tagged Mammalian cells Human His Thr25-Ser775
SEMA3E-14863M Recombinant Mouse SEMA3E Protein Mammalian Cell Mouse His
SEMA3E-4135Z Recombinant Zebrafish SEMA3E Mammalian Cell Zebrafish His
SEMA3E-5815C Recombinant Chicken SEMA3E Mammalian Cell Chicken His
SEMA3E-1907C Recombinant Chicken SEMA3E protein, His-tagged E.coli Chicken His Leu651~Asp740
SEMA3E-1908H Recombinant Human SEMA3E protein, His & T7-tagged E.coli Human His&T7 Arg32~Phe516
Sema3e-1909M Recombinant Mouse Sema3e protein, His-tagged E.coli Mouse His Ala581~Thr669
SEMA3E-4042H Recombinant Human SEMA3E Protein, His (Fc)-Avi-tagged HEK293 Human His&Fc&Avi
SEMA3E-4042H-B Recombinant Human SEMA3E Protein Pre-coupled Magnetic Beads HEK293 Human
SEMA3E-6715H Recombinant Human SEMA3E Protein (Arg32-Phe516), N-His tagged E.coli Human His Arg32-Phe516
SEMA3E-8004M Recombinant Mouse SEMA3E Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
SEMA3E-8004M-B Recombinant Mouse SEMA3E Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    SEMA3E involved in several pathways and played different roles in them. We selected most pathways SEMA3E participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEMA3E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance CXCL12,SHB,SCN4A,NRG3,HRAS,NRP1A,RHOGA,EPHB4B,SEMA6B,PTK2

    Protein Function

    SEMA3E has several biochemical functions, for example, chemorepellent activity,neuropilin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEMA3E itself. We selected most functions SEMA3E had, and list some proteins which have the same functions with SEMA3E. You can find most of the proteins on our site.

    Function Related Protein
    chemorepellent activity SEMA5A,SEMA3BL,SEMA3FA,UBE4A,SEMA3AB,SEMA3B,EFNA5,SEMA6A,SEMA3A,SEMA5B
    semaphorin receptor binding SEMA3AA,SEMA4D,SEMA6C,SEMA3BL,SEMA4A,SEMA6DL,SEMA3C,SEMA3GA,SEMA3D,SEMA6E
    neuropilin binding SEMA3FA,SEMA3G,SEMA3AB,SEMA4E,SEMA7A,SEMA3H,SEMA3BL,SEMA3GA,Sema3f,SEMA3C
    protein binding DHPS,VPS24,ZC3H11A,SYNGR1,EXOC7,PIP5K1A,PDLIM5,MDH1,CAPN3,ZNF2

    Interacting Protein

    SEMA3E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEMA3E here. Most of them are supplied by our site. Hope this information will be useful for your research of SEMA3E.

    PLXND1

    Resources

    Research Area

    Semaphorins, Plexin Receptors, and Related Molecules

    References

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