SCO1
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Official Full Name
SCO cytochrome oxidase deficient homolog 1 -
Overview
Mammalian cytochrome c oxidase (COX) catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. In yeast, 2 related COX assembly genes, SCO1 and SCO2 (synthesis of cytochrome c oxidase), enable subunits 1 and 2 to be incorporated into the holoprotein. This gene is the human homolog to the yeast SCO1 gene. -
Synonyms
SCO1;SCO cytochrome oxidase deficient homolog 1 (yeast);SCO (cytochrome oxidase deficient, yeast) homolog 1 , SCOD1;protein SCO1 homolog, mitochondrial;SCOD1
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SCO1-2540H | Recombinant Human SCO1, GST-tagged | E.coli | Human | GST | 1-301aa |
|
| SCO1-14769M | Recombinant Mouse SCO1 Protein | Mammalian Cell | Mouse | His |
|
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| SCO1-167H | Recombinant Human SCO1 protein, His-tagged | E.coli | Human | His | 132-301 a.a. |
|
| SCO1-168H | Recombinant Human SCO1 | E.coli | Human | Non | Full L. 32-301 a.a. |
|
| SCO1-2026HCL | Recombinant Human SCO1 293 Cell Lysate | HEK293 | Human | Non |
|
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| Sco1-5718M | Recombinant Mouse Sco1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
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| SCO1-6243H | Recombinant Human SCO1 Protein (Gly132-Ser301), N-GST tagged | E.coli | Human | GST | Gly132-Ser301 |
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| SCO1-763H | Recombinant Human SCO1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| SCO1-7941M | Recombinant Mouse SCO1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SCO1-7941M-B | Recombinant Mouse SCO1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
SCO1 involved in several pathways and played different roles in them. We selected most pathways SCO1 participated on our site, such as Electron Transport Chain,Gene Expression,Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ATP5L,C20orf7,UCP2,ATP5S,SLC25A14,NDUFAF6,ETFB,FAM36A,LRPPRC,SLC25A27 |
| Metabolism | HAS1,APOBB.1,ITPKB,GLYATL1,ARSH,IVD,SULT1B1,DHCR7,GPC5A,FABP12 |
| Electron Transport Chain | COX4I1,UCP3,UCP2,ATP5S,COX6A2,SLC25A14,COX17,COX8A,COX5B,NDUFS7 |
| Generic Transcription Pathway | ZNF649,ZNF839,SKIB,MED31,ZNF670,ZNF205,ZKSCAN4,NR4A2B,ZNF689,ZNF750 |
| Gene Expression | FARSB,METTL3,ZNF34,ZNF212,ZNF649,EFCAB11,ZNF713,PRDX2,GTF3AB,ZNF615 |
| TP53 Regulates Metabolic Genes | LRPPRC,COX16,SESN3,TACO1,PRDX2,SURF1,FAM36A,COX18,COX14 |
| The citric acid (TCA) cycle and respiratory electron transport | ATP5S,TIMMDC1,ETFDH,ADHFE1,C20orf7,PDK3B,MPC1,SLC25A14,SLC25A27,NDUFAF2 |
| Respiratory electron transport | NDUFAF4,LRPPRC,TACO1,SURF1,C2orf56,NDUFAF2,NDUFAF3,ETFA,COX18,FAM36A |
Protein Function
SCO1 has several biochemical functions, for example, copper ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SCO1 itself. We selected most functions SCO1 had, and list some proteins which have the same functions with SCO1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| copper ion binding | LOXL3B,DBH,ANG,TYRP1,HAMP,LOXL2,CUTC,SLC11A2,LOXL2B,SERPINB1A |
| protein binding | VAMP2,ALOX5,ZSCAN16,MMS19,CACNG1,CLN3,C1orf182,PPP2R2B,GRM6,C16orf79 |
Interacting Protein
SCO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SCO1.
NDUFS7;SLC25A13
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References
- Knowles, TT; Alleman, AR; et al. Characterization of the major antigenic protein 2 of Ehrlichia canis and Ehrlichia chaffeensis and its application for serodiagnosis of ehrlichiosis. CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY 10:520-524(2003).
- Galvez, F; Reid, SD; et al. Isolation and characterization of mitochondria-rich cell types from the gill of freshwater rainbow trout. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY 282:R658-R668(2002).
