SCN2A
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Official Full Name
sodium channel, voltage-gated, type II, alpha subunit -
Synonyms
HBA;NAC2;BFIC3;BFIS3;BFNIS;HBSCI;EIEE11;HBSCII;Nav1.2;SCN2A1;SCN2A2;Na(v)1.2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SCN2A-5569C | Recombinant Chicken SCN2A | Mammalian Cell | Chicken | His |
|
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| SCN2A-2030HCL | Recombinant Human SCN2A 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
SCN2A involved in several pathways and played different roles in them. We selected most pathways SCN2A participated on our site, such as Axon guidance,Developmental Biology,Interaction between L1 and Ankyrins, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCN2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Developmental Biology | LGI2A,LGI2B,BOC,EFNA3,SCN2B,ARPC5,NTN1A,FGF10B,CACNG8A,MED6 |
| Axon guidance | DLG3,PHB,FGF20A,NCAN,MAPK3,Ntng2,SEMA5A,EPHB4A,CNTN1,CDC42 |
| Interaction between L1 and Ankyrins | KCNQ3,KCNQ2,SCN3A,SCN8A,SCN2B,SCN3B,ANK2B,NADL1.1,SCN4A,SCN9A |
| L1CAM interactions | SCN8A,SCN4A,SCN9A,SDCBP,CNTN6,SCN2B,DCX,KIF4,NADL1.1,KIF4A |
Protein Function
SCN2A has several biochemical functions, for example, voltage-gated sodium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SCN2A itself. We selected most functions SCN2A had, and list some proteins which have the same functions with SCN2A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| voltage-gated sodium channel activity | HCN2,SCN4A,SCN8A,HCN4,SCN3B,SCN12AB,SCN11A,SCN5A,SCN12AA,SCN4AA |
Interacting Protein
SCN2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCN2A here. Most of them are supplied by our site. Hope this information will be useful for your research of SCN2A.
Dlg4;MPP3;RNF130;ARHGEF10L
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References
- Takenouchi, T; Iwamaru, Y; et al. Cytochalasin D enhances the accumulation of a protease-resistant form of prion protein in ScN2a cells: involvement of PI3 kinase/Akt signalling pathway. CELL BIOLOGY INTERNATIONAL 36:1223-1231(2012).
- Hara, H; Okemoto-Nakamura, Y; et al. Mouse Prion Protein (PrP) Segment 100 to 104 Regulates Conversion of PrPC to PrPSc in Prion-Infected Neuroblastoma Cells. JOURNAL OF VIROLOGY 86:5626-5636(2012).
