SCN1B
-
Official Full Name
sodium channel, voltage-gated, type I, beta subunit -
Overview
SCN1B is a single-pass type I membrane protein abundantly expressed in skeletal muscle, heart and brain. The SCN1B forms part of a heterotrimeric complex of voltage-gated sodium channels involved in the generation and propagation of action potentials in m -
Synonyms
SCN1B;sodium channel, voltage-gated, type I, beta subunit;sodium channel, voltage gated, type I, beta , sodium channel, voltage gated, type I, beta polypeptide;sodium channel subunit beta-1;sodium channel beta-1 subunit;GEFSP1
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Pan troglodytes
- Mus musculus
- Oryctolagus cuniculus (Rabbit)
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SCN1B-2535H | Recombinant Human SCN1B, GST-tagged | E.coli | Human | GST | C-term-186aa | |
| SCN1B-14754M | Recombinant Mouse SCN1B Protein | Mammalian Cell | Mouse | His |
|
|
| SCN1B-4099R | Recombinant Rhesus monkey SCN1B Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
|
|
| SCN1B-5261R | Recombinant Rat SCN1B Protein | Mammalian Cell | Rat | His |
|
|
| SCN1B-2031HCL | Recombinant Human SCN1B 293 Cell Lysate | HEK293 | Human | Non |
|
|
| RFL2056PF | Recombinant Full Length Pan Troglodytes Sodium Channel Subunit Beta-1(Scn1B) Protein, His-Tagged | E.coli expression system | Pan troglodytes | His | Full L. Full Length of Mature Protein (19-218) |
|
| RFL9555MF | Recombinant Full Length Mouse Sodium Channel Subunit Beta-1(Scn1B) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (19-218) |
|
| RFL9910OF | Recombinant Full Length Rabbit Sodium Channel Subunit Beta-1(Scn1B) Protein, His-Tagged | E.coli expression system | Oryctolagus cuniculus (Rabbit) | His | Full L. Full Length of Mature Protein (19-218) |
|
| SCN1B-3916R | Recombinant Rhesus Macaque SCN1B Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
|
|
| SCN1B-3916R-B | Recombinant Rhesus Macaque SCN1B Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
|
||
| SCN1B-48H | Recombinant Human SCN1B Protein, GST-tagged | Wheat Germ | Human | GST |
|
|
| SCN1B-4920R | Recombinant Rat SCN1B Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| SCN1B-4920R-B | Recombinant Rat SCN1B Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
||
| SCN1B-6782HF | Recombinant Full Length Human SCN1B Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 218 amino acids |
|
| SCN1B-7938M | Recombinant Mouse SCN1B Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| SCN1B-7938M-B | Recombinant Mouse SCN1B Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
SCN1B involved in several pathways and played different roles in them. We selected most pathways SCN1B participated on our site, such as Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCN1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adrenergic signaling in cardiomyocytes | ATF2,MYH7,ADRB2,CACNB4A,ATP1B4,ADRB2A,ADCY8,PPP2R2C,PPP2R3A,CALM |
Protein Function
SCN1B has several biochemical functions, for example, sodium channel inhibitor activity,sodium channel regulator activity,voltage-gated sodium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SCN1B itself. We selected most functions SCN1B had, and list some proteins which have the same functions with SCN1B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| voltage-gated sodium channel activity involved in cardiac muscle cell action potential | SCN2B,SCN3B,SCN5A |
| sodium channel regulator activity | SGK1,FGF12,SGK3,FXYD6,AGT,TMPRSS3,SCN2B,GPLD1,SCN1BB,FXYD3 |
| sodium channel inhibitor activity | CAMK2D,PCSK9,SLC14A2,NEDD4,NEDD4L |
| voltage-gated sodium channel activity involved in Purkinje myocyte action potential | SCN5A |
| voltage-gated sodium channel activity | SCN5A,SCN4AA,PKD2,SCN4A,SCN1BB,SCN12AB,SCN3A,SCN1A,SCN8AB,SCN3B |
Interacting Protein
SCN1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCN1B here. Most of them are supplied by our site. Hope this information will be useful for your research of SCN1B.
Resources
Related Services
Related Products
References
- Casini, S; Tan, HL; et al. Tubulin polymerization modifies cardiac sodium channel expression and gating. CARDIOVASCULAR RESEARCH 85:691-700(2010).
