SACM1L
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Official Full Name
SAC1 suppressor of actin mutations 1-like (yeast) -
Overview
Phosphatidylinositide phosphatase SAC1 is an enzyme that in humans is encoded by the SACM1L gene. -
Synonyms
SACM1L;SAC1 suppressor of actin mutations 1-like (yeast);phosphatidylinositide phosphatase SAC1;KIAA0851;SAC1;suppressor of actin 1;Suppressor of actin mutations 1-like protein
Recombinant Proteins
- Mouse
- Rhesus macaque
- Rat
- Pongo Abelii
- Mus musculus
- Human
- Xenopus laevis
- Bovine
- Mammalian Cell
- E.coli expression system
- HEK293
- HEK293T
- His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
SACM1L involved in several pathways and played different roles in them. We selected most pathways SACM1L participated on our site, such as Metabolism,Metabolism of lipids and lipoproteins,PI Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SACM1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PI Metabolism | ARF3,TPTE,SACM1LA,SACM1LB,PITPNB,FIG4 |
| Synthesis of PIPs at the ER membrane | SACM1LA,SACM1LB |
| Synthesis of PIPs at the Golgi membrane | TPTE,SACM1LB,SACM1LA,FIG4,ARF3 |
| Phospholipid metabolism | ABHD3,TPTE,PLD6,CEPT1,CPNE3,PITPNB,SACM1LB,CHKB,PNPLA8,SLC44A5B |
| Metabolism | NUBP1,DUT,GPAT2,NUDT4,PPM1L,TREH,FABP9,CYP46A1,SLC25A27,CYGB |
| Metabolism of lipids and lipoproteins | APOC2,DGAT1B,ABHD4,PITPNB,ARF3,SACM1LA,CDIPT,FABP11A,MED19,SREBF2 |
Protein Function
SACM1L has several biochemical functions, for example, 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity,IDP phosphatase activity,JUN kinase phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SACM1L itself. We selected most functions SACM1L had, and list some proteins which have the same functions with SACM1L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatase activity | DUSP22B,MTMR7A,CTDSPL2B,PPP1CC,DUSP27,CA3,C12orf5,ALP3,DUSP19A,DUSP22A |
| NADP phosphatase activity | SACM1LA,NT5DC3,CTDSPL2B,TENC1,PTPRQ,CTDSPL2A,PXYLP1,SACM1LB,SGPP2 |
| inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity | PXYLP1,TENC1,SGPP2,CTDSPL2B,CTDSPL2A,NT5DC3,SACM1LB,SACM1LA,PTPRQ |
| phosphohistidine phosphatase activity | PTPRQ,SACM1LA,SGPP2,SACM1LB,CTDSPL2B,PHPT1,TENC1,LHPP,PXYLP1,CTDSPL2A |
| 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity | SGPP2,PTPRQ,SACM1LA,PXYLP1,NT5DC3,SACM1LB,CTDSPL2A,TENC1,CTDSPL2B |
| JUN kinase phosphatase activity | PXYLP1,DUSP19,SACM1LA,NT5DC3,SACM1LB,CTDSPL2A,PTPRQ,TENC1,SGPP2,CTDSPL2B |
| inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity | PTPRQ,SACM1LB,CTDSPL2B,SGPP2,TENC1,NT5DC3,CTDSPL2A,PXYLP1,SACM1LA |
| transmembrane receptor protein phosphatase activity | PXYLP1,PTPRQ,CTDSPL2A,SACM1LB,SACM1LA,NT5DC3,CTDSPL2B,SGPP2,TENC1 |
| hydrolase activity | GNPDA1,LYZ2,TMPPE,GBP3,DCP1A,Gzmd,CNOT6,ATP8A1,DUSP13A,NUDT13 |
Interacting Protein
SACM1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SACM1L here. Most of them are supplied by our site. Hope this information will be useful for your research of SACM1L.
COPE;CLPX;RPN1;ATP5B;COPB2;DDOST;ARCN1;COPB1;COPA;COPZ1;EFR3A;Tmem173;LCOR;CDC5L;SMC4;COPG2;KLHDC2;COPG1
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