S1PR2
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Official Full Name
sphingosine-1-phosphate receptor 2 -
Synonyms
S1PR2;sphingosine-1-phosphate receptor 2;3169;ENSG00000175898;EDG5;H218;LPB2;S1P2;AGR16;EDG-5;Gpcr13;19p13.2;sphingosine 1-phosphate receptor 2;sphingosine 1-phosphate receptor 2;S1P receptor 2;S1P receptor EDG5;S1P receptor Edg-5;sphingosine 1-phosphate receptor Edg-5;endothelial differentiation G-protein coupled receptor 5;endothelial differentiation, sphingolipid G-protein-coupled receptor, 5
Recombinant Proteins
- Mouse
- Human
- Rat
- Zebrafish
- zebrafish
- Mus musculus
- Mammalian Cell
- HEK293
- E.coli expression system
- HEK293T
- In vitro E. coli expression system
- His
- Myc&DDK
- His&Fc&Avi
Involved Pathway
S1PR2 involved in several pathways and played different roles in them. We selected most pathways S1PR2 participated on our site, such as Sphingolipid signaling pathway,Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with S1PR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Sphingolipid signaling pathway | GNAI2,GNAI3,SGMS2,TRADD,GNAI1,HRAS,BCL2,PRKCE,PPP2R3C,PRKCZ |
| Neuroactive ligand-receptor interaction | PTGFR,OPRD1A,P2RX6,PTGER3,MTNR1A,HRH4,GRIA2,GRIN2D,CHRNA4B,GABRD |
Protein Function
S1PR2 has several biochemical functions, for example, G-protein coupled receptor activity,G-protein coupled receptor binding,integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S1PR2 itself. We selected most functions S1PR2 had, and list some proteins which have the same functions with S1PR2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | NCOA1,APOBEC1,HDAC1,FERMT2,GFM2,MAP3K8,FZD5,BCCIP,SNCG,GPR85 |
| G-protein coupled receptor activity | PRLHR,OLFCG2,VMN1R45,CXCR3.1,OR2K2,LPHN1,OLFR480,FZD10,OR2F1,FZD8B |
| lipid binding | CYTH2,SEC14L4,EPN1,FABP7A,UNC119B,DBI,SH3GL3,PPARD,APODA.2,PPP5C |
| integrin binding | TIMP2,ACTN3,COL4A3,DMP1,WISP1B,EGFL6,TSPAN8,LYN,TNN,ACTN1 |
| G-protein coupled receptor binding | GNAI2B,HSPA1A,RLN3,PROK2,NPFFL,GNAI2,FYN,GNAT3,GPRC5B,PSAP |
| sphingosine-1-phosphate receptor activity | S1PR3A,S1PR5,S1PR5A,SPHK2,GPR6,S1PR4,SPHK1,S1PR3,S1PR5B,S1PR1 |
Interacting Protein
S1PR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S1PR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of S1PR2.
ITGB4;S1PR1
Resources
Research Area
Endothelial Cell Development MoleculesEndothelial Cell Markers
Endothelial Cell Differentiation Markers
Bioactive Lipid G Protein-Coupled Receptors
Related Services
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References
- Moriyama, S; Takahashi, N; et al. Sphingosine-1-phosphate receptor 2 is critical for follicular helper T cell retention in germinal centers. JOURNAL OF EXPERIMENTAL MEDICINE 211:1297-1305(2014).
- Tanaka, K; Hashizume, M; et al. Anti-interleukin-6 receptor antibody prevents systemic bone mass loss via reducing the number of osteoclast precursors in bone marrow in a collagen-induced arthritis model. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 175:172-180(2014).
