RTN3
-
Official Full Name
reticulon 3 -
Overview
This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
RTN3;reticulon 3;reticulon-3;ASY interacting protein;ASYIP;HAP;homolog of ASY protein;isoforme III;neuroendocrine specific protein like 2;NSP like protein II;NSPL2;NSPLII;RTN3 A1;Reticulon3;NSP-like protein 2;OTTHUMP00000237754;OTTHUMP00000237755;OTTHUMP00000237756;OTTHUMP00000237757;OTTHUMP00000237759;NSP-like protein II;neuroendocrine-specific protein-like 2;neuroendocrine-specific;RTN3-A1
Recombinant Proteins
- Zebrafish
- Rat
- Human
- Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
- Mouse
- Mammalian Cell
- HEK293
- E.coli expression system
- Yeast
- E.coli
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RTN3-11298Z | Recombinant Zebrafish RTN3 | Mammalian Cell | Zebrafish | His |
|
|
| RTN3-5194R | Recombinant Rat RTN3 Protein | Mammalian Cell | Rat | His |
|
|
| RTN3-2122HCL | Recombinant Human RTN3 293 Cell Lysate | HEK293 | Human | Non |
|
|
| RFL7004XF | Recombinant Full Length Xenopus Tropicalis Reticulon-3(Rtn3) Protein, His-Tagged | E.coli expression system | Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) | His | Full L. Full Length (1-213) |
|
| RTN3-4853R | Recombinant Rat RTN3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| RTN3-4853R-B | Recombinant Rat RTN3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
||
| Rtn3-5633M | Recombinant Mouse Rtn3 protein, His-tagged | Yeast | Mouse | His | 182-440aa |
|
| Rtn3-6474M | Recombinant Mouse Rtn3 protein, His-tagged | E.coli | Mouse | His | 182-440aa |
|
Involved Pathway
RTN3 involved in several pathways and played different roles in them. We selected most pathways RTN3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RTN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RTN3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RTN3 itself. We selected most functions RTN3 had, and list some proteins which have the same functions with RTN3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RPL23,MYH7B,NAPB,AHR,FAM53C,NEFL,KLHL35,MYO1E,SMURF2,BACE1 |
Interacting Protein
RTN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RTN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RTN3.
PTPN9;346157;CDIPT;SNX1;PTPN9;PPP2R3C
Resources
Related Services
Related Products
References
