RRAS2
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Official Full Name
related RAS viral (r-ras) oncogene homolog 2 -
Overview
This gene encodes a member of the R-Ras subfamily of Ras-like small GTPases. The encoded protein associates with the plasma membrane and may function as a signal transducer. This protein may play an important role in activating signal transduction pathways that control cell proliferation. Mutations in this gene are associated with the growth of certain tumors. Pseudogenes of this gene are found on chromosomes 1 and 2. Alternate splicing results in multiple transcript variants. -
Synonyms
RRAS2;related RAS viral (r-ras) oncogene homolog 2;ras-related protein R-Ras2;TC21;ras-like protein TC21;teratocarcinoma oncogene
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Rhesus macaque
- E.coli
- Mammalian Cell
- Insect Cell
- HEK293
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
RRAS2 involved in several pathways and played different roles in them. We selected most pathways RRAS2 participated on our site, such as MAPK signaling pathway,Ras signaling pathway,cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RRAS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tight junction | LLGL1,VAPAL,CRB3A,JAM2,MYL2,MYH11A,CLDNK,AKT3A,MYL2B,MYH1A |
| Proteoglycans in cancer | PRKACA,MAP2K2,Ctsl,PAK1,PPP1CC,MMP9,ERBB4,ITGB1,PPP1CB,ITPR1 |
| Phospholipase D signaling pathway | KIT,AVP,SHC2,GRM5,GRM3,DGKD,PLA2G4C,Kitl,PIK3R3,PDGFD |
| cAMP signaling pathway | PDE3A,BDNF,PDE4B,VAV3,GRIN3A,FSHB,EP300,TSHR,GNAI3,CAMK4 |
| Ras signaling pathway | GAB1,PLA2G2D,PLCG1,PLA2G10,GNGT2,NGF,CDC42,GNG13,FGF14,RIN1 |
| Regulation of Actin Cytoskeleton | ARHGEF6,FN1,BDKRB1,FGF22,PAK6,RHOAB,CHRM5A,FGF12A,FGFR2,INS |
| MAPK signaling pathway | MINK1,MAPKAPK2,GNG12A,DUSP8A,RAF1,PTPN7,PPM1NB,FGF11,MAP3K7,BRAF |
| HTLV-I infection | IL1R2,XPO1,CD3E; CD3D,ATF4,KRAS,HLA-DRB3,CALR,CREM,CRTC3,HLA-A |
Protein Function
RRAS2 has several biochemical functions, for example, GTP binding,GTPase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RRAS2 itself. We selected most functions RRAS2 had, and list some proteins which have the same functions with RRAS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | BATF3,USP14,HIST1H2AH,KRT25,MOB4,RBM39,NME7,PDE6H,MAPK4,HAGH |
| GTPase activity | TUBB5,ATL2,RAB18A,EEF1A1,RHEB,RAB8B,REM2,RAB9A,RAB14L,RAB5AA |
| GTP binding | DNM2,RAB25,RALBB,RAB28,EFTUD1,ACSM1,GEM,RSG1,ARHGAP5,RASL10A |
Interacting Protein
RRAS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RRAS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RRAS2.
Fnta;RIN1;Tubb4b;Trim69;CREB3;RAF1;ARAF;XRCC6;LGALS4;TRAF2;RALGDS;Rassf5
RRAS2 Related Signal Pathway
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