RRAGC
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Official Full Name
Ras-related GTP binding C -
Overview
The mTORC1 kinase complex is a critical regulator of cell growth. Its activity is modulated by energy levels, growth factors, and amino acids via signaling through Akt, MAPK, and AMPK pathways. Recent studies found that the four related GTPases, RagA, Rag -
Synonyms
RRAGC;Ras-related GTP binding C;ras-related GTP-binding protein C;FLJ13311;GTR2;TIB929;Rag C protein;GTPase-interacting protein 2;RAGC
Recombinant Proteins
- Mouse
- Chicken
- Human
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RRAGC-14517M | Recombinant Mouse RRAGC Protein | Mammalian Cell | Mouse | His |
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| RRAGC-2585C | Recombinant Chicken RRAGC | Mammalian Cell | Chicken | His |
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| RRAGC-5551H | Recombinant Human Ras-Related GTP Binding C, His-tagged | E.coli | Human | His |
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| RRAGC-2146HCL | Recombinant Human RRAGC 293 Cell Lysate | HEK293 | Human | Non |
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| Rragc-5621M | Recombinant Mouse Rragc Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| RRAGC-7808M | Recombinant Mouse RRAGC Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RRAGC-7808M-B | Recombinant Mouse RRAGC Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RRAGC involved in several pathways and played different roles in them. We selected most pathways RRAGC participated on our site, such as mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RRAGC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mTOR signaling pathway | AKT2,RPS6KA3A,PIK3CD,IRS1,RRAGCB,PTEN,TSC1A,PRKCBB,INS,RHEB |
Protein Function
RRAGC has several biochemical functions, for example, GDP binding,GTP binding,GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RRAGC itself. We selected most functions RRAGC had, and list some proteins which have the same functions with RRAGC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | PPP2R4,USF2,PIK3R2,HIST1H2BN,BIRC5,AHR,TAF12,UGT1A1,DRD1A,MYF6 |
| protein binding | GCC2,MC4R,SCFD1,MYRIP,SPG20,RIPK1L,SPG11,IFNAR1,H2AFZ,CLK1 |
| GTP binding | TUBG2,TPX2,IIGP1,ARL13A,TUBB4B,RAB23,ARHGAP5,ARF4,RHOGB,ARF6 |
| GDP binding | GNAI1,RAB7,RAN,RAP2C,ARL8B,RAB2A,ARL3,RAB7L1,RAB35,RAB22A |
| magnesium ion binding | SPHK1,NEK6,GSS,ENO4,ATP8A1,FARS2,ITPK1A,STK4,PTENB,PIF1 |
| GTPase activity | RHOD,TUBA3C,GNAIA,TUBA8L4,RAB42B,NKIRAS2,GNAI2B,TUBA8L,TUBB1,RAB39A |
Interacting Protein
RRAGC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RRAGC here. Most of them are supplied by our site. Hope this information will be useful for your research of RRAGC.
RRAGA;RRAGB
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References
- Oloumi, A; Lam, W; et al. Identification of genes differentially expressed in V79 cells grown as multicell spheroids. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 78:483-492(2002).
- Vlahou, G; Elias, M; et al. The Ras related GTPase Miro is not required for mitochondrial transport in Dictyostelium discoideum. EUROPEAN JOURNAL OF CELL BIOLOGY 90:342-355(2011).
