RPN2
-
Official Full Name
ribophorin II -
Overview
This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
RPN2;ribophorin II;dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2;RIBIIR;RPN II;RPNII;SWP1;ribophorin-2;dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit;RPN-II
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- Rat
- Mus musculus
- Pongo Abelii
- Sus scrofa (Pig)
- Bovine
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- E.coli expression system
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- Fc
- Myc&DDK
- His&Fc&Avi
Involved Pathway
RPN2 involved in several pathways and played different roles in them. We selected most pathways RPN2 participated on our site, such as N-Glycan biosynthesis,Metabolic pathways,Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| N-Glycan biosynthesis | ALG2,FUT8,MAN2A1,DPM1,DAD1,MGAT1A,DPAGT1,ALG1,MGAT4C,B4GALT2 |
| Protein processing in endoplasmic reticulum | UBE2D4,RRBP1A,RAD23A,TRAM1,NFE2L2,UBE2G1B,CANX,ATXN3L,TXNDC5,CUL1 |
| Metabolic pathways | ALDH1A1,LCT,SDS,CYP1A,GCDHA,ALP3,ZNRD1,PCYT1BB,P4HA1,AGPAT6 |
Protein Function
RPN2 has several biochemical functions, for example, contributes_to dolichyl-diphosphooligosaccharide-protein glycotransferase activity,ribosome binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPN2 itself. We selected most functions RPN2 had, and list some proteins which have the same functions with RPN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to dolichyl-diphosphooligosaccharide-protein glycotransferase activity | OSTC,TUSC3,DDOST,RPN1,DAD1,STT3A |
| ribosome binding | EIF6,EIF5A,CPEB1,ETF1A,CPEB1B,CPEB4,HSPA5,ERI1,EIF2S1,OLA1 |
Interacting Protein
RPN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPN2.
ESR1;SAP18;NME2;MAGEA6;ARF6;CLN3;TSC22D1;NDRG1;C20orf24;TMBIM4;BRE;TNIK;GSTK1;PHLDA3;NGFR;RHOA;RBBP4;EZH2;FBN3
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