RHOT1
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Official Full Name
ras homolog gene family, member T1 -
Overview
Mitochondrial Rho GTPase 1 is an enzyme that in humans is encoded by the RHOT1 gene. -
Synonyms
RHOT1;ras homolog gene family, member T1;ARHT1;mitochondrial Rho GTPase 1;FLJ11040;MIRO 1;ARHT 1;FLJ12633;hMiro 1;hMiro1;MIRO1;Mitochondrial Rho 1;Mitochondrial Rho1;Rac GTP binding protein like protein;Ras homolog gene family member T1;Rhot 1;hMiro-1;rac-GTP binding protein-like protein;rac-GTP-binding protein-like protein;MIRO-1
Recombinant Proteins
- Human
- Chicken
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&SUMO
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RHOT1-261H |
Active Recombinant Human RHOT1 protein, His-tagged
|
E.coli | Human | His | 186-591 a.a. |
|
| RHOT1-1357C | Recombinant Chicken RHOT1 | Mammalian Cell | Chicken | His |
|
|
| RHOT1-14178M | Recombinant Mouse RHOT1 Protein | Mammalian Cell | Mouse | His |
|
|
| RHOT1-1506HCL | Recombinant Human RHOT1 cell lysate | Human | Non |
|
||
| RHOT1-2027C | Recombinant Chicken RHOT1 Protein (1-219 aa), His-SUMO-tagged | E.coli | Chicken | His&SUMO | 1-219 aa |
|
| RHOT1-7592M | Recombinant Mouse RHOT1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| RHOT1-7592M-B | Recombinant Mouse RHOT1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
RHOT1 involved in several pathways and played different roles in them. We selected most pathways RHOT1 participated on our site, such as Rho GTPase cycle,Signal Transduction,Signaling by Rho GTPases, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling by Rho GTPases | DEPDC7,PRC1B,OPHN1,RTKN,ARHGAP17A,ARHGEF17,FMNL1,ARHGAP23,RHOT2,ARHGEF18A |
| Rho GTPase cycle | ARHGAP26,STARD13,TAGAPB,ARHGAP32,DCLRE1B,ARHGAP19,MYO9B,OPHN1,GMIP,ARHGAP12B |
| Signal Transduction | LGR5,AKR1C6,CRABP2,OPN4,ABI1A,TAS2R3,KLHL12,RGS11,BOC,ASH2L |
Protein Function
RHOT1 has several biochemical functions, for example, GTP binding,GTPase activity,calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOT1 itself. We selected most functions RHOT1 had, and list some proteins which have the same functions with RHOT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP binding | GMPPAA,RAB11AL,GFM2,GNA15,EEF1A1,SEPT12,RAB7A,RND1L,SEPT11,RAB21 |
| GTPase activity | SRPR,RAB1BA,RRAD,GTPBP4,ATL3,RAB39B,TUBA8L3,GNAIA,RHOJ,DIRAS1 |
| molecular_function | LRG1,CRYBB1L2,C2orf28,FNDC3C1,TEX22,DESI1A,GUCD1,ACSM3,GM5136,OR2A4 |
| protein binding | RALY,MFAP1,GADD45A,EMP1,FKBP7,CRYBA4,NIPAL3,SIGIRR,LAPTM5,ALS2 |
| calcium ion binding | MMP14,PCDH2G17,PCDHGB3,SYT3,EGFL8,PCDH2G3,PCDH17,CMLC1,MYL4,DGKB |
Interacting Protein
RHOT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOT1.
TRAK1;Kif5c;PARK2;KIF5C;PINK1;Trak2
Resources
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References
- Klinck, R; Laberge, G; et al. Alternative splicing in osteoclasts and Paget's disease of bone. BMC MEDICAL GENETICS 15:-(2014).
- Ahmad, T; Mukherjee, S; et al. Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy. EMBO JOURNAL 33:994-1010(2014).
