RHOQ

Official Full Name

ras homolog gene family, member Q
Overview

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14.
Synonyms

RHOQ;ras homolog gene family, member Q;ARHQ, RAS like, family 7, member A , RASL7A;rho-related GTP-binding protein RhoQ;TC10;ARHQ;Ras homolog gene family member Q;RAS like family 7 member A;Ras like protein family member 7A;Ras like protein TC10;Ras related GTP binding protein TC10;Ras-like protein family member 7A;Ras-like protein TC10;RASL7A;Rho related GTP binding protein RhoQ;RHOQ_HUMAN;TC10A;RAS-like, family 7, member A

Recombinant Proteins

Type:

Recombinant Proteins

Cell & Tissue Lysates

Protein Pre-coupled Magnetic Beads

Filters:

Species

Human
Zebrafish
Rat
Chicken

Source

E.coli
Mammalian Cell
HEK293

Tag

His
His&GST
Non
His&Fc&Avi
GST

Cat.#	Product name	Source (Host)	Species	Tag	Protein Length	Price
RHOQ-2296H	Recombinant Human RHOQ, His-tagged	E.coli	Human	His	1-205aa	$319 / 25μg
RHOQ-10198Z	Recombinant Zebrafish RHOQ	Mammalian Cell	Zebrafish	His		Inquiry
RHOQ-1192H	Recombinant Human RHOQ protein, His & GST-tagged	E.coli	Human	His&GST	Met1~Cys202	Inquiry
RHOQ-5037R	Recombinant Rat RHOQ Protein	Mammalian Cell	Rat	His		Inquiry
RHOQ-566H	Recombinant Human ras homolog family member Q, His-tagged	E.coli	Human	His	1-202 a.a.	Inquiry
RHOQ-6031C	Recombinant Chicken RHOQ	Mammalian Cell	Chicken	His		Inquiry
RHOQ-2347HCL	Recombinant Human RHOQ 293 Cell Lysate	HEK293	Human	Non		Inquiry
RHOQ-4696R	Recombinant Rat RHOQ Protein, His (Fc)-Avi-tagged	HEK293	Rat	His&Fc&Avi		Inquiry
RHOQ-4696R-B	Recombinant Rat RHOQ Protein Pre-coupled Magnetic Beads	HEK293	Rat			Inquiry
RHOQ-5774H	Recombinant Human RHOQ Protein (Met1-Cys202), N-GST tagged	E.coli	Human	GST	Met1-Cys202	Inquiry

Involved Pathway

RHOQ involved in several pathways and played different roles in them. We selected most pathways RHOQ participated on our site, such as Insulin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Insulin signaling pathway	PIK3R2,SHC4,PTPN1,G6PC3,FBP1A,PPP1CAA,MKNK2,INS,GYS1,FLOT2B

Protein Function

RHOQ has several biochemical functions, for example, GBD domain binding,GTP binding,GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOQ itself. We selected most functions RHOQ had, and list some proteins which have the same functions with RHOQ. You can find most of the proteins on our site.

Function	Related Protein
GTPase activity	EIF2S3,RAB8B,TUBA3C,RAB18B,TUBA8L3,RHOT1A,RHOT1,DNM1A,EEF2,ARL3
profilin binding	CYFIP1,CTTN,PCLO,DIAPH1,WIPF1,FMNL1,HTT,EVL,VASP,DIAP1
GTP binding	RAB1BB,RAB42B,GTPBP10,ARFIP2,EIF2B1,RABL5,RSG1,RHOV,DNM2B,ARL4D

Interacting Protein

RHOQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOQ here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOQ.

WAS;PAK1;CDC42BPA;CDC42BPG