RGS19
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Official Full Name
regulator of G-protein signaling 19 -
Overview
G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. -
Synonyms
RGS19;regulator of G-protein signaling 19;regulator of G protein signalling 19;GAIP;RGSGAIP;G alpha interacting protein;GNAI3IP;Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein;G-alpha-interacting protein;G protein signalling regulator 19;regulator of G-protein signalling 19
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- T7
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
RGS19 involved in several pathways and played different roles in them. We selected most pathways RGS19 participated on our site, such as Calcium Regulation in the Cardiac Cell,G alpha (i) signalling events,G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G alpha (i) signalling events | SOUL3,DRD4,DRD3,OPN1SW,ADORA1,ADRA2C,ADRA2A,GPR55A,CCR9,TAS2R7 |
| Myometrial Relaxation and Contraction Pathways | RGS20,RGS4,GABPA,GUCA2B,RAMP3,ADM,IGFBP2,RGS7,ACTA1,MAFF |
| GPCR downstream signaling | SCT,CYSLTR1,MGLL,PRKCHB,ANXA1,SSTR5,NMB,VIP,PTHLH,QRFPR |
| G alpha (q) signalling events | LPAR1,FPR-RS4,TRIO,MLN,MGLL,PMCH,OPN4.1,LPAR2A,EDN1,CHRM1 |
| G alpha (z) signalling events | RGS20,ADRA2B,RGS17,RGS4,ADRA2C,ADRA2A |
| Neurotrophic factor-mediated Trk receptor signaling | GIPC1,RIT2,RIT1,MCF2L,DYNLT1,FAIM |
| Calcium Regulation in the Cardiac Cell | CX55.5,CHRM4,CASQ1B,GJA5,GJB3,GJB2,RGS4,GJA10,GJA8,GJC2 |
| Gastrin-CREB signalling pathway via PKC and MAPK | GCGA,NMS,MGLL,PROKR1,EDN2,FPR-RS3,OPN4,NMBA,TAC2,RASGRP2 |
Protein Function
RGS19 has several biochemical functions, for example, G-protein alpha-subunit binding,GTPase activator activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS19 itself. We selected most functions RGS19 had, and list some proteins which have the same functions with RGS19. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | TBC1D24,GIT2,PLCB1,ARHGAP9,RALBP1,RASA3,AXIN1,OPHN1,TBC1D3B,CHML |
| protein binding | PHOSPHO2,GSG1L,TBC1D1,PCBD2,GPC3,RPF1,GLP1R,IDE,MYCBP,DACT1 |
| G-protein alpha-subunit binding | AGTR1A,LPAR1,ARHGEF11,PPP5C,HTR2A,OPRM1,LPAR3,RIC8B,DRD1A,NUCB1 |
Interacting Protein
RGS19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS19 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS19.
Gnai3;GNAI2;MAPK6;q81s67_bacan;MZT1
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