RGMB
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Official Full Name
repulsive guidance molecule family member B -
Overview
Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. -
Synonyms
RGMB;repulsive guidance molecule family member B;DRAGON;1110059F19Rik;RGM domain family member B;RGM domain family, member B;repulsive guidance molecule B;DRG11-responsive axonal guidance and outgrowth of neurite
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Rhesus macaque
- HEK293
- Mammalian cells
- Mammalian Cell
- Fc
- His
- Flag
- His&Fc&Avi
Involved Pathway
RGMB involved in several pathways and played different roles in them. We selected most pathways RGMB participated on our site, such as Axon guidance,BMP receptor signaling,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGMB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| BMP receptor signaling | NOG,CHRDL1,RGMA,CTDSPL,SOSTDC1,AHSG,CALML4,CTDSP1,HFE2,GREM1 |
| Netrin-1 signaling | UNC5D,RNF8,PITPNA,TRPC4,NTN1A,RGMA,SIAH2,EZRA,TRPC5,HFE2 |
| Axon guidance | EPHB2,CDK5R1B,CSF2RA,EFNB3,RNF8,PLXND1,RGS3,DUSP2,MYL12B,NRP1 |
| Developmental Biology | DPYSL3,RASGRP4,DUSP4,TCF4,EPHA2,JAK1,COL4A3,CSNK2B,EFNA1B,TCF3B |
Protein Function
RGMB has several biochemical functions, for example, coreceptor activity,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RGMB itself. We selected most functions RGMB had, and list some proteins which have the same functions with RGMB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| identical protein binding | TRIM55,ADIPOQ,MMP9,EIF2AK3,TPRG1L,S100A4,MCM10,ITGB3,SAFB2,PCNA |
| coreceptor activity | RAMP1,CCR8,RAMP3,CCR5,IGSF1,CD86,CD80,ACVR2A,CD28,CD8B |
Interacting Protein
RGMB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGMB here. Most of them are supplied by our site. Hope this information will be useful for your research of RGMB.
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