RFC1
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Official Full Name
replication factor C (activator 1) 1, 145kDa -
Overview
A1 (also designated Bfl-1) is a Bcl-2 family protein that dimerizes with both Bcl-2 and Bax, and has been identified as a hematopoietic- specific, early inducible gene. Although A1 demonstrated properties similar to those of Bcl-2, its function may be mor -
Synonyms
RFC1;replication factor C (activator 1) 1, 145kDa;replication factor C (activator 1) 1 (145kD);replication factor C subunit 1;A1;MHCBFB;PO GA;RFC140;A1 140 kDa subunit;RF-C 140 kDa subunit;activator 1 subunit 1;replication factor C1;MHC bindin
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- E. coli
- Mammalian Cell
- Wheat Germ
- E.coli
- Yeast
- Insect Cell
- His
- GST
- His&Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| RFC1-001H | Recombinant Human RFC1 Protein, His-tagged | E. coli | Human | His | 800-1093 aa | |
| RFC1-1595C | Recombinant Chicken RFC1 | Mammalian Cell | Chicken | His |
|
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| RFC1-5591Z | Recombinant Zebrafish RFC1 | Mammalian Cell | Zebrafish | His |
|
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| RFC1-01H | Recombinant Human RFC1 Protein, GST-tagged | Wheat Germ | Human | GST |
|
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| RFC1-2319H | Recombinant Human RFC1 Protein (402-492 aa), His-Myc-tagged | E.coli | Human | His&Myc | 402-492 aa |
|
| RFC1-2394H | Recombinant Human RFC1 Protein (402-492 aa), His-tagged | Yeast | Human | His | 402-492 aa |
|
| RFC1-2807H | Recombinant Human RFC1 Protein (402-492 aa), His-Myc-tagged | Insect Cell | Human | His&Myc | 402-492 aa |
|
Involved Pathway
RFC1 involved in several pathways and played different roles in them. We selected most pathways RFC1 participated on our site, such as DNA replication,Nucleotide excision repair,Mismatch repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with RFC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| DNA Replication | GINS1,MCM6,GINS2,POLE4,RFC4,MCM5,CDT1,MCM2,GMNN,LIG1 |
| Mismatch repair | MSH3,MLH1,SSBP1,RFC5,MSH6,PCNA,RPA2,MLH3,POLD1,PMS2 |
| Nucleotide Excision Repair | USP45,INO80,GTF2H2C,POLE3,GTF2H5,COPS5,RBX1,XPA,RPA2,GTF2H2C_2 |
Protein Function
RFC1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by RFC1 itself. We selected most functions RFC1 had, and list some proteins which have the same functions with RFC1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
RFC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RFC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RFC1.
Resources
Related Services
Related Products
References
- Rupasree, Y; Naushad, SM; et al. Epigenetic modulation of RFC1, MHC2TA and HLA-DR in systemic lupus erythematosus: Association with serological markers and six functional polymorphisms of one-carbon metabolic pathway. GENE 536:45-52(2014).
- Nunez, MI; Behrens, C; et al. High Expression of Folate Receptor Alpha in Lung Cancer Correlates with Adenocarcinoma Histology and Mutation. JOURNAL OF THORACIC ONCOLOGY 7:833-840(2012).
