REXO2
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Official Full Name
REX2, RNA exonuclease 2 homolog (S. cerevisiae) -
Overview
This gene encodes a 3-to-5 exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. -
Synonyms
REXO2;REX2, RNA exonuclease 2 homolog (S. cerevisiae);oligoribonuclease, mitochondrial;CGI 114;DKFZP566E144;SFN;1810038D15Rik;AW107347;MGC105914;MGC111570;Oligoribonuclease, mitochondrial [Precursor];RFN;RNA exonuclease 2 homolog;Small fragment nuclease;Smfn;REX2;CGI-114
Recombinant Proteins
- Mouse
- Rhesus macaque
- Human
- Rat
- Chicken
- Cynomolgus
- Mammalian Cell
- Wheat Germ
- E.coli
- HEK293
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
REXO2 involved in several pathways and played different roles in them. We selected most pathways REXO2 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with REXO2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome biogenesis in eukaryotes | FBL,SPATA5,BMS1,HEATR1,WDR43,PWP2H,NOP10,CIRH1A,RBM28,UTP14A |
Protein Function
REXO2 has several biochemical functions, for example, 3-5 exonuclease activity,3-5-exoribonuclease activity,nucleic acid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by REXO2 itself. We selected most functions REXO2 had, and list some proteins which have the same functions with REXO2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3-5 exonuclease activity | MRE11A,RAD9,RAD9A,WRN,EXD2,APLF,TREX1,POLG,POLE,REV3L |
| nucleic acid binding | ZNF728,RBM12B2,SCAND3,ZFP637,CHD6,FAM200A,SSX2,RNASEL3,ZFP110,RNASE2 |
| 3-5-exoribonuclease activity | DOM3Z,ISG20,EXOSC5,ERI3,CNOT8,EXOSC2,ERI2,DIS3,DIS3L,USB1 |
Interacting Protein
REXO2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with REXO2 here. Most of them are supplied by our site. Hope this information will be useful for your research of REXO2.
EIF1B;MCC;MPG;ATG5;TRAF6
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