RCN2
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Official Full Name
reticulocalbin 2, EF-hand calcium binding domain -
Overview
The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. -
Synonyms
RCN2;reticulocalbin 2, EF-hand calcium binding domain;reticulocalbin-2;E6BP;ERC 55;ERC55;Reticulocalbin 2;EF hand calcium binding domain (endoplasmic reticulum calcium binding protein;55kD);TCBP49;Calcium binding protein ERC 55;Calcium-binding protein ERC-55;E6 binding protein;E6-binding protein;RCN2_HUMAN;Reticulocalbin 2 EF hand calcium binding domain (endoplasmic reticulum calcium binding protein 55kD);Reticulocalbin 2, EF hand calcium binding domain;reticulocalbin 2, EF-hand calcium binding domain (endoplasmic reticulum calcium-binding protein, 55kD);ERC-55
Recombinant Proteins
- Mouse
- Zebrafish
- Human
- Rat
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Rcn2-704M | Recombinant Mouse Rcn2 Protein, His-tagged | E.coli | Mouse | His | Ser26~Ser301 | |
| RCN2-14036M | Recombinant Mouse RCN2 Protein | Mammalian Cell | Mouse | His |
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| RCN2-3343Z | Recombinant Zebrafish RCN2 | Mammalian Cell | Zebrafish | His |
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| RCN2-3496H | Recombinant Human RCN2, His-tagged | E.coli | Human | His |
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| RCN2-4976R | Recombinant Rat RCN2 Protein | Mammalian Cell | Rat | His |
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| RCN2-5546C | Recombinant Chicken RCN2 | Mammalian Cell | Chicken | His |
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| RCN2-1487HCL | Recombinant Human RCN2 cell lysate | Human | Non |
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| RCN2-257H | Recombinant Human RCN2 protein, His-tagged | HEK293 | Human | His | Gly23-Leu317 |
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| RCN2-4635R | Recombinant Rat RCN2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| RCN2-4635R-B | Recombinant Rat RCN2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| RCN2-7500M | Recombinant Mouse RCN2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| RCN2-7500M-B | Recombinant Mouse RCN2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
RCN2 involved in several pathways and played different roles in them. We selected most pathways RCN2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RCN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
RCN2 has several biochemical functions, for example, calcium ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RCN2 itself. We selected most functions RCN2 had, and list some proteins which have the same functions with RCN2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | CLEC3B,OTOFA,PCDHGC5,TPT1,PVALB,SLIT1A,CHP2,MMP10,EFCAB6,PCDH2AB5 |
| protein binding | ALPP,OAS1,BST2,C1QTNF3,GPR37,IGFN1,TFAP2A,CRYBA4,ADORA1,LRRC4 |
Interacting Protein
RCN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RCN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RCN2.
GABARAPL2;TRAF6;E6;E6;E6;a8k1f4_human;TNFRSF1A;TNFRSF1B;MLF1;Cbx1;MDM2;TRAF1;MAP3K1;RIPK1;TRADD;Trim28
Resources
Related Services
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References
- Suzuki, N; Ban, S; et al. Calcium-dependent structural changes in human reticulocalbin-1. JOURNAL OF BIOCHEMISTRY 155:281-293(2014).
- Jung, DH; Mo, SH; et al. Calumenin, a multiple EF-hands Ca2+-binding protein, interacts with ryanodine receptor-1 in rabbit skeletal sarcoplasmic reticulum. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 343:34-42(2006).
