Porcn
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Official Full Name
porcupine homolog (Drosophila)
Recombinant Proteins
- Mouse
- Zebrafish
- Human
- Mammalian Cell
- HEK293
- Insect Cell
- His
- Non
- Flag
- Flag&GFP
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PORCN-13131M | Recombinant Mouse PORCN Protein | Mammalian Cell | Mouse | His |
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| PORCN-6768Z | Recombinant Zebrafish PORCN | Mammalian Cell | Zebrafish | His |
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| PORCN-492HCL | Recombinant Human PORCN lysate | HEK293 | Human | Non |
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| PORCN-07H | Recombinant Human PORCN-TEV-GFP Protein (M1-G461 end, remove 219-228aa, C187A, A194S, K231G, R232T, K233M, A234V), C-Flag-tagged | Insect Cell | Human | Flag | M1-G461 end, remove 219-228aa, C187A, A194S, K231G, R232T, K233M, A234V |
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| PORCN-0911H | Recombinant Human PORCN Protein (M1-G461 end, remove 219-228aa, C187A, A194S, K231G, R232T, K233M, A234V), GFP-Flag tagged | Insect Cell | Human | Flag&GFP | M1-G461 end, remove 219-228aa, C187A, A194S, K231G, R232T, K233M, A234V |
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| PORCN-6947M | Recombinant Mouse PORCN Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PORCN-6947M-B | Recombinant Mouse PORCN Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Porcn involved in several pathways and played different roles in them. We selected most pathways Porcn participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Porcn were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt signaling pathway | SFRP1,LRP6,SOX17,TBL1X,TP53,WNT11B,SFRP5,CAMK2G,PPP3CA,SFRP2 |
Protein Function
Porcn has several biochemical functions, for example, Wnt-protein binding,palmitoleoyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Porcn itself. We selected most functions Porcn had, and list some proteins which have the same functions with Porcn. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Wnt-protein binding | LRP5L,FZD3,FZD3B,SFRP2,FZD2,LRP2A,ROR2,FZD1,FZD7A,CTHRC1 |
Interacting Protein
Porcn has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Porcn here. Most of them are supplied by our site. Hope this information will be useful for your research of Porcn.
Resources
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References
- Bankhead, EJ; Colasanto, MP; et al. Multiple Requirements of the Focal Dermal Hypoplasia Gene Porcupine during Ocular Morphogenesis. AMERICAN JOURNAL OF PATHOLOGY 185:197-213(2015).
- Miranda, M; Galli, LM; et al. Identification of the WNT1 residues required for palmitoylation by Porcupine. FEBS LETTERS 588:4815-4824(2014).
