PTPRJ
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Official Full Name
protein tyrosine phosphatase, receptor type, J -
Overview
CD148, a receptor-like protein tyrosine phosphatase also known as human protein tyrosine phosphatase-eta (HPTP-eta) or density-enhanced protein tyrosine phosphatase-1 (DEP-1), is involved in signal transduction in leucocytes and is thought to contribute t -
Synonyms
PTPRJ;protein tyrosine phosphatase, receptor type, J;receptor-type tyrosine-protein phosphatase eta;CD148;DEP1;HPTPeta;DEP-1;R-PTP-J;HPTP eta;CD148 antigen;density-enhanced phosphatase 1;protein-tyrosine phosphatase eta;human density enhanced phosphatase-1;protein-tyrosine phosphatase receptor type J;susceptibility to colon cancer 1, mouse, homolog of;protein tyrosine phosphatase, receptor type, J polypeptide;SCC1;R-PTP-ETA
Recombinant Proteins
- Rhesus macaque
- Human
- Chicken
- Mouse
- Rat
- HEK293
- E.coli
- Mammalian Cell
- HEK293T
- Insect cells
- Non
- Fc
- hIgG4
- GST
- His
- His&T7
- Myc&DDK
- N-SUMO & N-His
Involved Pathway
PTPRJ involved in several pathways and played different roles in them. We selected most pathways PTPRJ participated on our site, such as Adherens junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPRJ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Adherens junction | PVRL3,ACTN2,LMO7,ACTN1,SRC,NLK,FYNB,WASLB,INSRA,RHOAC |
Protein Function
PTPRJ has several biochemical functions, for example, beta-catenin binding,delta-catenin binding,gamma-catenin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPRJ itself. We selected most functions PTPRJ had, and list some proteins which have the same functions with PTPRJ. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
gamma-catenin binding | CDH1,LEF1,Fert2,TCF7L2,DSG1A,CDH2,PTPRK,FER,PTBP3,APC |
delta-catenin binding | PLEKHA7A,CDH24,DACT2,PLEKHA7,DACT1,DACT3 |
platelet-derived growth factor receptor binding | PTEN,PDGFRA,PDGFA,PDGFAA,PDGFRB,Pdgfa&Pdgfb,ITGB3,FIGF,LYN,PDGFC |
phosphatase activity | CTDNEP1B,DUSP11,CTDSPL2B,CTDSPL2A,PTPRJA,MTMR1A,SACM1LA,DUSP23B,DUSP3B,SACM1LB |
beta-catenin binding | TBL1XR1,HDAC6,SALL1,NF2,APC2,KLF4,KDM6B,CDH5,GRIP1,SMAD3 |
protein kinase binding | PARP1,FAF1,NGFRAP1,PPP1CB,CCNB3,CCND1,AP2A2,FGFR1OP,NIPAL1,JIP1 |
protein tyrosine phosphatase activity | DUSP22,SSH2B,TIMM50,PTPRK,DUSP8A,PTPRR,DUPD1,DUSP13,PTPN6,PTPN9 |
mitogen-activated protein kinase binding | GTF2I,TNIP1,NBR1,TPR,MAPK7,ARRB2,DUSP2,ABL1,MICALCL,MAPKAPK5 |
protein binding | MARK4,DGKQ,GNB2,STRADA,GPRASP2,LRRFIP2,VDR,MED7,SKIV2L2,RNF31 |
Interacting Protein
PTPRJ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPRJ here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPRJ.
MET;CTNND1;PDGFRB;MAPK3;KDR
Resources
Research Area
Phosphatases and RegulatorsGranulocyte Markers
Phosphatases in the Akt Pathway
Adherens Junction Proteins in Endothelial Cells
CD Antigen (Granulocyte Markers)
Monocyte Markers
Related Services
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References