PTPRG

  • Official Full Name

    protein tyrosine phosphatase, receptor type, G

  • Overview

    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.

  • Synonyms

    PTPRG;protein tyrosine phosphatase, receptor type, G;PTPG;receptor-type tyrosine-protein phosphatase gamma;RPTPG;H RG317H01.1;HPTPG;Protein tyrosine phosphatase gamma;Protein tyrosine phosphatase receptor type G;Protein tyrosine phosphatase receptor type gamma polypeptide;Protein-tyrosine phosphatase gamma;PTPgamma;PTPRG protein;PTPRG_HUMAN;R PTP Gamma;R-PTP-gamma;Receptor type protein phosphatase gamma;Receptor type tyrosine protein phosphatase gamma;Receptor tyrosine phosphatase gamma;H_RG317H01.1;OTTHUMP00000213232;OTTHUMP00000213233;receptor-type protein phosphatase gamma;receptor type protein tyrosine phosphatase gamma;protein tyrosine phosphatase, receptor type, gamma polypeptide

Recombinant Proteins

  • Human
  • Chicken
  • E.coli
  • Mammalian Cell
  • His
  • Non
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
PTPRG-2063H Recombinant Human PTPRG, His-tagged E.coli Human His 20-333aa
PTPRG-1305H Recombinant Human Protein Tyrosine Phosphatase, Receptor Type, G E.coli Human Non 801-1147 a.a.
PTPRG-30355TH Recombinant Human PTPRG E.coli Human Non 801-1147 a.a.
PTPRG-459H Recombinant Human PTPRG, GST-tagged E.coli Human GST 801-1147 a.a.
PTPRG-5887C Recombinant Chicken PTPRG Mammalian Cell Chicken His
PTPRG-0841H Recombinant Human PTPRG Protein (P820-N1130), Tag Free E.coli Human Non P820-N1130
PTPRG-0842H Recombinant Human PTPRG Protein (P820-N1130), His tagged E.coli Human His P820-N1130

    Involved Pathway

    PTPRG involved in several pathways and played different roles in them. We selected most pathways PTPRG participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPRG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    PTPRG has several biochemical functions, for example, identical protein binding,protein binding,protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPRG itself. We selected most functions PTPRG had, and list some proteins which have the same functions with PTPRG. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ARMCX5-GPRASP2,UCHL5,ABT1,SNAP23,HNRNPUL1,PLK2,TP53,VCAN,PTPN4,OIT3
    transmembrane receptor protein tyrosine phosphatase activity PTPRS,PTPRC,EVLA,PTPRE,PTPRA,PTPRM,PTPRR,PTPN6,PTPRB,PTPRUB
    identical protein binding ATG16L1,DDX58,LECT2,BNIP2,CLDN23,AGXT2L2,COL2A1,DYNLT1A,DRD2,SHANK1
    protein tyrosine phosphatase activity MTMR2,PTPRFB,DUSP2,PTPRR,MTMR7B,MTMR3,DUSP11,PTPRF,PTPDC1,PTPN2B

    Interacting Protein

    PTPRG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPRG here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPRG.

    CTNNB1;PDPK1;ERBB2;NTRK1;INSR;LCK;MET;PDGFRB;CDH2;EPOR;CBL;MAPK3;TIE1;CSK;TEC;WAS

    Resources

    Research Area

    Phosphatases and Regulators

    References

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