PSMD3

  • Official Full Name

    proteasome (prosome, macropain) 26S subunit, non-ATPase, 3

  • Overview

    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid.

  • Synonyms

    PSMD3;proteasome (prosome, macropain) 26S subunit, non-ATPase, 3;tissue specific transplantation antigen 2 , TSTA2;26S proteasome non-ATPase regulatory subunit 3;P58;Rpn3;S3;26S proteasome non ATPase regulatory subunit 3;26S proteasome regulatory subunit RPN3;26S proteasome regulatory subunit S3;OTTHUMP00000164347;Proteasome (prosome, macropain) 26S subunit non ATPase 3;Proteasome subunit p58;PSMD3_HUMAN;Tissue specific transplantation antigen 2;TSTA2

Recombinant Proteins

  • Zebrafish
  • Mouse
  • Chicken
  • Human
  • Rhesus macaque
  • Mammalian Cell
  • Wheat Germ
  • HEK293
  • In Vitro Cell Free System
  • HEK293T
  • His
  • Non
  • His&Fc&Avi
  • Myc&DDK
Cat.# Product name Source (Host) Species Tag Protein Length Price
PSMD3-10851Z Recombinant Zebrafish PSMD3 Mammalian Cell Zebrafish His
PSMD3-13594M Recombinant Mouse PSMD3 Protein Mammalian Cell Mouse His
PSMD3-3015C Recombinant Chicken PSMD3 Mammalian Cell Chicken His
PSMD3-30427TH Recombinant Human PSMD3 Wheat Germ Human Non 100 amino acids
PSMD3-30428TH Recombinant Human PSMD3 Wheat Germ Human Non 534 amino acids
PSMD3-3671R Recombinant Rhesus monkey PSMD3 Protein, His-tagged Mammalian Cell Rhesus macaque His
PSMD3-2749HCL Recombinant Human PSMD3 293 Cell Lysate HEK293 Human Non
PSMD3-3489R Recombinant Rhesus Macaque PSMD3 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
PSMD3-3489R-B Recombinant Rhesus Macaque PSMD3 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
PSMD3-408HF Recombinant Full Length Human PSMD3 Protein In Vitro Cell Free System Human Full L. 534 amino acids
Psmd3-5194M Recombinant Mouse Psmd3 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
PSMD3-6294H Recombinant Human PSMD3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
PSMD3-7222M Recombinant Mouse PSMD3 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
PSMD3-7222M-B Recombinant Mouse PSMD3 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PSMD3 involved in several pathways and played different roles in them. We selected most pathways PSMD3 participated on our site, such as Proteasome,Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Epstein-Barr virus infection HLA-DQA1,PIK3CG,EIF2AK2,PLCG2,TRP53,NUP214,POLR2J3,POLR2C,NFKBIE,EIF2AK3
    Proteasome PSMB10,PSMA4,PSMD7,PSME4,PSMA7,PSMA6,PSMD4B,PSMD12,PSMB5,PSMC1A

    Protein Function

    PSMD3 has several biochemical functions, for example, enzyme regulator activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD3 itself. We selected most functions PSMD3 had, and list some proteins which have the same functions with PSMD3. You can find most of the proteins on our site.

    Function Related Protein
    enzyme regulator activity PSMD2,BRCC3,EIF2B1,SEPT2,PPP1R7,CPN2,RAB3GAP2,PSMD1,DPM2,APOC3
    protein binding CD69,FBXO18,KLRG1,CALCRL,SLC9A3,HTR1A,PPP2R5A,SKP1,DDX41,DCBLD2

    Interacting Protein

    PSMD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD3.

    UCHL5;PSMD14;ZBTB43;SHFM1;CEP44;VCAM1;PLCG2

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