PPP5C
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Official Full Name
protein phosphatase 5, catalytic subunit -
Overview
Protein phosphatase 5 (PP5) is a member of the serine/threonine phosphatase family that also includes PP1, PP2A and PP2B. PP5 uniquely contains an amino-terminal regulatory domain with three tetratricopeptide repeat (TPR) motifs and a carboxy-terminal cat -
Synonyms
PPP5C;protein phosphatase 5, catalytic subunit;PPP5;serine/threonine-protein phosphatase 5;PP5;PP-T;protein phosphatase T;PPT;FLJ36922;FLJ55954
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Rat
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- GST
- Non
- His
- His&Myc
- His&Fc&Avi
Involved Pathway
PPP5C involved in several pathways and played different roles in them. We selected most pathways PPP5C participated on our site, such as MAPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP5C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MAPK signaling pathway | TGFB3,JIP1,TGFBR2,IL1B,NFATC1,FGF2,CACNB1,CACNB2,GRB2B,CDC42L |
Protein Function
PPP5C has several biochemical functions, for example, G-protein alpha-subunit binding,RNA binding,heat shock protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP5C itself. We selected most functions PPP5C had, and list some proteins which have the same functions with PPP5C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZNF498,PPM1LB,ARSH,TRIM55A,ZNF740B,CYP2C55,ZBED2,ZFP239,RBM22,ZBED1 |
| identical protein binding | SNCA,TNPO3,CIDEB,DPP4,PTEN,ADIPOQ,MLL1,TRIM39,GRIN3A,GRIK5 |
| G-protein alpha-subunit binding | HTR2B,F2RL1,RGS14,HTR2A,RGS19,LPAR3,RIC8A,RGS4,RIC8,F2R |
| heat shock protein binding | TOMM34,PPID,BAK1,APAF1,DNAJA2,DNAJC9,KCNJ11,HDAC2,FKBP5,HSPA1L |
| microtubule binding | CEP350,LC3,MAPRE3B,KIFC1,CHD4,SKA2,KIF5AA,CLASP1,KIF12,CCDC88A |
| lipid binding | FAM123A,YBX2,APODB,CLINT1,HDLBP,PPARD,RASGRP2,PCYT1A,SH3GL1,APOL3 |
| RNA binding | RPLP2,CLUHA,ADAD1,KHDC3L,RBMX,RNASEH1,SETD1BA,PSMA1,HNRNPC,ZBP1 |
| protein binding | ADAMTS4,PRTFDC1,TRIM24,CDC42BPG,RAB3IP,SIVA1,PEPD,FRS2,KIF1B,HMGB2 |
| phosphoprotein phosphatase activity | PTPREB,PHPT1,PPP4CB,PPM1DA,PPAP2B,PTPN4B,CTDNEP1,PPP1CC,PPEF2,DLGAP5 |
Interacting Protein
PPP5C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP5C here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP5C.
HSP90AA1;HSP90AB1;ESR1;CDC37
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References
- You, S; Piali, L; et al. Therapeutic Use of a Selective S1P(1) Receptor Modulator Ponesimod in Autoimmune Diabetes. PLOS ONE 8:-(2013).
- Fusco, DN; Brisac, C; et al. A Genetic Screen Identifies Interferon-alpha Effector Genes Required to Suppress Hepatitis C Virus Replication. GASTROENTEROLOGY 144:1438-U210(2013).
