PPP2R5C
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Official Full Name
protein phosphatase 2, regulatory subunit B, gamma -
Overview
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
PPP2R5C;protein phosphatase 2, regulatory subunit B, gamma;protein phosphatase 2, regulatory subunit B (B56), gamma isoform , protein phosphatase 2, regulatory subunit B, gamma isoform;serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform;B56G;PR61G;2A5G_HUMAN;B alpha regulatory subunit;IMYPNO1;KIAA0044;MGC23064;PP2A B subunit B gamma isoform;PP2A B subunit B56 gamma isoform;PP2A B subunit isoform B-gamma;PP2A B subunit isoform B56-gamma;PP2A B subunit isoform PR61-gamma;PP2A B subunit isoform R5-gamma;PP2A B subunit PR61 gamma isoform;PP2A B subunit R5 gamma isoform;PP2A subunit B B gamma isoform;PP2A subunit B B55 gamma isoform;PP2A subunit B PR55 gamma isoform;PP2A subunit B R2 gamma isoform;Protein phosphatase 2 regulatory subunit B (B56) gamma isoform;Protein phosphatase 2 regulatory subunit B gamma;Renal carcinoma antigen NY REN 29;Renal carcinoma antigen NY-REN-29;Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform;Serine/threonine protein phosphatase 2A 56 kDa regulatory subunit gamma isoform;OTTHUMP00000246562;OTTHUMP00000246563;OTTHUMP00000246564;OTTHUMP00000246565;OTTHUMP00000246642;OTTHUMP00000246643;PP2
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PPP2R5C-1920H | Recombinant Human PPP2R5C, GST-tagged | E.coli | Human | GST | N-term-384aa | |
| PPP2R5C-13263M | Recombinant Mouse PPP2R5C Protein | Mammalian Cells | Mouse | His |
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| PPP2R5C-29538TH | Recombinant Human PPP2R5C | Wheat Germ | Human | Non | 100 amino acids |
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| PPP2R5C-3521C | Recombinant Chicken PPP2R5C | Mammalian Cells | Chicken | His |
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| PPP2R5C-2916HCL | Recombinant Human PPP2R5C 293 Cell Lysate | HEK293 | Human | Non |
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| PPP2R5C-2917HCL | Recombinant Human PPP2R5C 293 Cell Lysate | HEK293 | Human | Non |
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| Ppp2r5c-5080M | Recombinant Mouse Ppp2r5c Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| PPP2R5C-7039M | Recombinant Mouse PPP2R5C Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PPP2R5C-7039M-B | Recombinant Mouse PPP2R5C Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PPP2R5C involved in several pathways and played different roles in them. We selected most pathways PPP2R5C participated on our site, such as mRNA surveillance pathway,Sphingolipid signaling pathway,Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP2R5C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Sphingolipid signaling pathway | MAPK9,SGMS1,PRKCG,PLCB3,PLCB2,GNAI1,LASS4,SGMS2,PIK3CB,RAF1 |
| Adrenergic signaling in cardiomyocytes | PPP2R1A,PIK3CA,PRKACG,CACNA1DA,CAMK2B,AGTR2,PRKCA,ADRB2,CREB3L1,ATP1B1A |
| PIK-Akt signaling pathway | MAP2K1,FLT4,GNB4,OSMR,IKBKG,TLR4,INS,Gh,IFNA17,Kitl |
| mRNA surveillance pathway | PPP2R1B,PELO,WDR33,MAGOHB,SMG1,PPP2R2BB,CASC3,PABPC1,FIP1L1,PPP1CBL |
| Oocyte meiosis | YWHAH,BTRC,CAMK2D2,CALM3A,CUL1,CALM4,MAD2L1,CCNB1,CAMK2A,ADCY1B |
| Dopaminergic synapse | CLOCK,DRD3,PPP3CC,DDC,CAMK2G,GNB1,SCN1A,PRKACA,GRIA4,ARNTL |
| AMPK signaling pathway | PFKFB2,PPP2CB,IRS1,PRKAB1,IGF1,PPP2CA,PRKAG1,LEP,IGF1R,CD36 |
Protein Function
PPP2R5C has several biochemical functions, for example, protein binding,protein phosphatase type 2A regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP2R5C itself. We selected most functions PPP2R5C had, and list some proteins which have the same functions with PPP2R5C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CIB1,DDX23,NIPSNAP1,IL32,ADRM1,GTF2H2,PAK2,RUVBL2,ARF6,MELK |
| protein phosphatase type 2A regulator activity | PPP2R2B,PPP2R1B,PPP2R3A,PPP2R2BB,SET,ENSAA,pab1,IGBP1,PPP2R5EB,ENSA |
Interacting Protein
PPP2R5C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP2R5C here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP2R5C.
PPP2CA;PPP2R1A;TP53;PPP2R1B
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References
- Kitabatake, M; Toda, T; et al. Transgenic Overexpression of G5PR That Is Normally Augmented in Centrocytes Impairs the Enrichment of High-Affinity Antigen-Specific B Cells, Increases Peritoneal B-1a Cells, and Induces Autoimmunity in Aged Female Mice. JOURNAL OF IMMUNOLOGY 189:1193-1201(2012).
- Skalnikova, H; Vodicka, P; et al. Protein signaling pathways in differentiation of neural stem cells. PROTEOMICS 8:4547-4559(2008).
