PPARD
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Official Full Name
PPARD peroxisome proliferator-activated receptor delta -
Synonyms
PPARD;peroxisome proliferator-activated receptor delta;peroxisome proliferative activated receptor, delta;FAAR;NR1C2;NUC1;NUCII;PPAR-beta;PPAR-delta;nuclear hormone receptor 1;nuclear receptor subfamily 1 group C member 2;peroxisome proliferator-activated receptor beta;peroxisome proliferator-activated nuclear receptor beta/delta variant 2;NUCI;PPARB;MGC3931
Recombinant Proteins
- Human
- Mouse
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- Mamanlian cells
- HEK293T
- Non
- His
- GST
- His&MBP
- Myc&DDK
- Flag
- His&Fc&Avi
Involved Pathway
PPARD involved in several pathways and played different roles in them. We selected most pathways PPARD participated on our site, such as PPAR signaling pathway,Wnt signaling pathway,Pathways in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPARD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PPAR signaling pathway | SCD,ILK,RXRAA,PDPK1B,ACOX3,PLTP,ACSL4B,DBI,Scd2,CYP4A14 |
| Pathways in cancer | BIRC5,PIK3CG,VEGFC,RALB,FGF3,PDGFB,KITLG,MLH1,WNT8A,WNT3 |
| Wnt signaling pathway | FZD2,PRICKLE2B,MAPK8A,NLK2,TCF7,PLCB1,AXIN1,MMP7,CCND3,SMAD4 |
| Acute myeloid leukemia | STAT5A,IKBKB,PIM1,PIK3CB,LEF1,RUNX1T1,MAP2K1,NRAS,PML,SPI1 |
Protein Function
PPARD has several biochemical functions, for example, DNA binding,RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding,drug binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPARD itself. We selected most functions PPARD had, and list some proteins which have the same functions with PPARD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein heterodimerization activity | PVRL1,HIST1H2AA,HMG20A,XBP1,USF2,DMRT1,BRAF,ZBTB1,ADD1,TIRAP |
| steroid hormone receptor activity | NR2F5,PPARDB,RXRAB,RARAB,ESRRGB,NR1H4,NR1H2,NR1D1,PPARA,NR1D2B |
| RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding | NR1H4,PPARAA,RORAB,VDRA,STAT3,NR2E3,PPARDB,RORCA,RORB,RORA |
| DNA binding | IRF1,CDK5R2,ZNF705B,MYCA,ZNF239,FOXN1,SSH3,DUX3,MKXA,EF1 |
| sequence-specific DNA binding | HOXB8B,THRA,FOXG1B,HOXD10A,SPIB,NANOGP8,FOXM1,ATF6B,HOXC6A,TBX5A |
| transcription factor activity, sequence-specific DNA binding | MESPBA,TGIF2,FOXD1,ZNF501,FOXL1,ZIC3,HOXA3,NEUROD1,ZFP354C,ZNF397 |
| drug binding | TLR7,MT3,SETD6,HTR1B,ACE,HTR2C,TLR8,CHRNA3,HTR2B,SMO |
| lipid binding | RUFY1,SH3GL3,APOH,FFAR1,CPTP,PPARA,CYTH1,FABP10A,PTGS2,LPAR3 |
| zinc ion binding | Car2,ZDHHC15A,MLLT6,NR2C1,BRF1A,MEX3C,CXXC1A,ZPR1,AMFR,Ar |
Interacting Protein
PPARD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPARD here. Most of them are supplied by our site. Hope this information will be useful for your research of PPARD.
KDM1A;HSP90AB1;HDAC2;SMAD9;PRMT3
Resources
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References
- Sahebkar, A; Chew, GT; et al. Recent advances in pharmacotherapy for hypertriglyceridemia. PROGRESS IN LIPID RESEARCH 56:47-66(2014).
- Nava-Villalba, M; Aceves, C; et al. 6-Iodolactone, key mediator of antitumoral properties of iodine. PROSTAGLANDINS & OTHER LIPID MEDIATORS 112:27-33(2014).
