POLR3K

  • Official Full Name

    polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa

  • Overview

    This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17.

  • Synonyms

    POLR3K;polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa;polymerase (RNA) III (DNA directed) polypeptide K (12.3 kDa);DNA-directed RNA polymerase III subunit RPC10;RPC11;DNA directed RNA polymerase III subunit K;DNA directed RNA polymerase III subunit RPC10;DNA directed RNA polymerases III 12.5 kDa polypeptide;hRPC11;HsC11p;My010;RNA polymerase III subunit C10;RNA polymerase III subunit C11;OTTHUMP00000067145;RNA polymerase III subunit CII;RNA polymerase III 12.5 kDa subunit;RNA polymerase III subunit (hRPC11);DNA-directed RNA polymera;C11;RPC10;RPC12.5;C11-RNP3

Recombinant Proteins

  • Human
  • Zebrafish
  • Mouse
  • E.coli
  • Mammalian Cell
  • HEK293
  • HEK293T
  • Insect cells
  • E. coli
  • GST
  • His
  • Non
  • Myc&DDK
  • His&SUMO
Cat.# Product name Source (Host) Species Tag Protein Length Price
POLR3K-1852H Recombinant Human POLR3K, GST-tagged E.coli Human GST 1-108aa
POLR3K-266H Recombinant Human POLR3K, His-tagged E.coli Human His 1-108aa
POLR3K-674Z Recombinant Zebrafish POLR3K Mammalian Cell Zebrafish His
POLR3K-3020HCL Recombinant Human POLR3K 293 Cell Lysate HEK293 Human Non
POLR3K-1482H Recombinant Human POLR3K Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
POLR3K-3355H Recombinant Human POLR3K protein, His-SUMO-tagged E.coli Human His&SUMO 1-108aa
POLR3K-4756H Recombinant Human POLR3K protein, His-tagged Insect cells Human His 1-108aa
Polr3k-5009M Recombinant Mouse Polr3k Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
POLR3K-7996H Recombinant Human POLR3K protein E. coli Human Non 108aa

    Involved Pathway

    POLR3K involved in several pathways and played different roles in them. We selected most pathways POLR3K participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR3K were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA polymerase ZNRD1,POLR3D,POLR3GL,POLR3E,POLR2J,POLR2D,POLR2G,POLR3GLB,POLR2EB,POLR2J2
    Cytosolic DNA-sensing pathway RIPK1L,POLR3GL,OSTN,LOC100033925,IFNA6,CCL4,IFNA4,TMEM173,IL33,POLR3C
    Metabolic pathways PAH,PLA2G4C,PLA2G6,AKR1A1A,GBGT1L4,CDIPT,MTMR7B,ITPA,DNMT4,GLULB
    Purine metabolism POLR2J2,POLR3GLB,PDE5AB,POLR2B,NPR2,NME1-NME2,GDA,ADAL,NME2B.1,PDE9A
    Epstein-Barr virus infection SHFM1,HLA-E,RELA,HDAC5,MAPK13,PIK3CB,TYK2,EIF2AK4,HSPA1B,PSMD3
    Pyrimidine metabolism ITPA,UCK1,ENTPD8,DUT,CMPK2,NT5C1AA,POLE4,UCK2,POLA1,NT5C2

    Protein Function

    POLR3K has several biochemical functions, for example, DNA binding,DNA-directed RNA polymerase activity,contributes_to RNA polymerase III activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR3K itself. We selected most functions POLR3K had, and list some proteins which have the same functions with POLR3K. You can find most of the proteins on our site.

    Function Related Protein
    zinc ion binding RNF150,MAP3K7IP3,Car8,KPNB1,GTF2H2C_2,TP53I3,ADAMTS9,RFFL,ISL1,TCF19
    DNA binding SOX21A,HELZ2,TBL1XR1,GSX1,HOXB8B,RORCA,MLL1,GFI1B,MGAA,ZNF34
    contributes_to RNA polymerase III activity POLR2L,POLR2E,POLR3G,POLR3GLA,POLR1C,POLR2K,POLR2F,POLR3C,POLR3GL,CRCP
    DNA-directed RNA polymerase activity MED20,POLR2EB,POLR3A,POLR3B,POLR2A,POLR3H,POLR3C,CCDC111,MED21,POLR3G

    Interacting Protein

    POLR3K has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR3K here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR3K.

    Ruvbl1;POLR2F;POLR3E

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All POLR3K Products

    Required fields are marked with *

    My Review for All POLR3K Products

    Required fields are marked with *