POLR2I

  • Official Full Name

    polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa

  • Overview

    This gene encodes a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit, in combination with two other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity.

  • Synonyms

    POLR2I;polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa;polymerase (RNA) II (DNA directed) polypeptide I (14.5kD);DNA-directed RNA polymerase II subunit RPB9;hRPB14.5;RPB9;DNA directed RNA polymerase II 14.5 kDa polypeptide;DNA directed RNA polymerase II polypeptide I;DNA directed RNA polymerase II subunit I;DNA directed RNA polymerase II subunit RPB9;Polymerase (RNA) II (DNA directed) polypeptide I 14.5kDa;RNA polymerase II subunit B9;RPB14.5;RNA polymerase II 14.5 kDa subunit;DNA-directed RNA polymerase II subunit I;DNA-directed RNA polymerase II 14.5 kDa polypeptide

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • Rhesus macaque
  • E.coli
  • Mammalian Cell
  • HEK293
  • E. coli
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
POLR2I-1847H Recombinant Human POLR2I, GST-tagged E.coli Human GST 1-125aa
POLR2I-13099M Recombinant Mouse POLR2I Protein Mammalian Cell Mouse His
POLR2I-1530Z Recombinant Zebrafish POLR2I Mammalian Cell Zebrafish His
POLR2I-30766TH Recombinant Human POLR2I E.coli Human Non Full L. 1-125 a.a.
POLR2I-3518R Recombinant Rhesus monkey POLR2I Protein, His-tagged Mammalian Cell Rhesus macaque His
POLR2I-389H Recombinant Human polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa, His-tagged E.coli Human His 1-125 a.a.
POLR2I-522H Recombinant Human POLR2I, His-tagged E.coli Human His
POLR2I-8463H Recombinant Human POLR2I, His-tagged E.coli Human His
POLR2I-490HCL Recombinant Human POLR2I lysate HEK293 Human Non
POLR2I-3336R Recombinant Rhesus Macaque POLR2I Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
POLR2I-3336R-B Recombinant Rhesus Macaque POLR2I Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
POLR2I-5644H Recombinant Human POLR2I protein, His-tagged E. coli Human His 140aa(including fusion tag)
POLR2I-6926M Recombinant Mouse POLR2I Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
POLR2I-6926M-B Recombinant Mouse POLR2I Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    POLR2I involved in several pathways and played different roles in them. We selected most pathways POLR2I participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR2I were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Purine metabolism POLR2J,Adcy4,POLR1B,PDE7B,ENPP3,GUCY2E,ADSS,PDE5AB,DGUOK,CANT1A
    Pyrimidine metabolism ZNRD1,NT5C1AA,NT5C1B,udp,POLR2D,CTPS2,POLR1D,UCK1,RRM2,CTPS1A
    Metabolic pathways LIPCA,FUT9,CYP26C1,NDUFC1,CRYL1,UGT2A1,INPP4A,LDHC,HYAL4,GBA
    RNA polymerase POLR2D,POLR1A,POLR2G,POLR1B,POLR3GLB,POLR2J2,POLR2A,TWISTNB,POLR2K,ZNRD1
    Epstein-Barr virus infection TRP53,PIK3CA,PRKACA,TRAF6,YWHAZ,EIF2AK2,HSPB2,PIK3CB,PIK3R3,IRF3
    Huntingtons disease ATP5H,SLC25A31,PPARGC1A,COX8C,VDAC3,UQCRB,SOD1,NDUFS5,EP300,COX7C

    Protein Function

    POLR2I has several biochemical functions, for example, DNA binding,DNA-directed RNA polymerase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR2I itself. We selected most functions POLR2I had, and list some proteins which have the same functions with POLR2I. You can find most of the proteins on our site.

    Function Related Protein
    DNA-directed RNA polymerase activity CRCP,MED20,POLR2E,POLR2GL,POLR2D,PRIM2,POLR2J,POLR2EB,POLR3A,POLR2A
    DNA binding ZFAND3,ORC6L,IRF7,UBTFL1,ZNF615,MED26,SUPT6H,KDM5D,SATB1A,ISL2B
    zinc ion binding MBTD1,TRIM55A,TRIM45,ADAM5P,SIRT3,SRSF7A,ZDHHC15,USP49,RNF169,OTUD7B

    Interacting Protein

    POLR2I has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR2I here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR2I.

    MED19;MED26;WDR48;TBCD;ssrna_ag;SUPT5H;POLR2F;POLR2G;Gtf2b;MED10;Rprd1b;PCIF1;MED29;CDKN2AIP

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