PNOC
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Official Full Name
PNOC prepronociceptin -
Overview
Nociceptin is the ligand of the opioid receptor-like receptor (OPRL1). It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development. -
Synonyms
PNOC;prepronociceptin;nocistatin;PPNOC;nociceptin;propronociceptin
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- His
- His&T7
- Non
- His&Fc&Avi
Involved Pathway
PNOC involved in several pathways and played different roles in them. We selected most pathways PNOC participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (i) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with PNOC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signal Transduction | SDR9C7,DEPDC7,NEDD8,EMR4,PROKR1,RTKN,MDKB,GRAP,INTU,C |
| Signaling by GPCR | GPR37B,PENKB,CNR2,OPN1SW1,SOUL3,S1PR5B,RCA2.1,GPR55,NTS,TAAR1 |
| G alpha (i) signalling events | HEBP1,PNOCB,CCL35.1,ADRA2B,OPN5,APPB,OXGR1A.3,GPR18,OXGR1A.2,OPN1SW1 |
| GPCR ligand binding | GCGA,TAAR1,GAL,OXER1,TAS2R7,NMB,LPAR2B,CCRL2,CXCR6,RGS1 |
| GPCR downstream signaling | RGS14,TAC3,PTHRP2,OXGR1A.3,OPN4B,OXER1,TAS2R7,S1PR5B,PLEKHG2,OPN1LW |
| Class A/1 (Rhodopsin-like receptors) | DRD2,CYSLTR1,AMCF-II,PROKR1A,LTB4R,GPR37B,NMBB,CCR6,OXGR1,INSL3 |
| Peptide ligand-binding receptors | KISS1,APLNR,PROKR1A,MLN,GPR37B,NTS,CX3CR1,SSTR4,SST,INSL3 |
Protein Function
PNOC has several biochemical functions, for example, neuropeptide hormone activity,opioid peptide activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PNOC itself. We selected most functions PNOC had, and list some proteins which have the same functions with PNOC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| opioid peptide activity | PENK,CDC42EP2,ZFP106,PDYN |
| protein binding | SERPINA1A,ROR2,TMEM182,BICD1,GLYAT,NKX2-5,BNIP2,MAP3K4,GNL3L,GPN3 |
| neuropeptide hormone activity | NPPA,CORT,CRH,AVP,POMCA,GAL,AGRP,PYY,PENK,VIP |
Interacting Protein
PNOC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PNOC here. Most of them are supplied by our site. Hope this information will be useful for your research of PNOC.
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