PLIN3
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Official Full Name
perilipin 3 -
Overview
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
PLIN3;perilipin 3;PP17;TIP47;M6PRBP1;mannose-6-phosphate receptor binding protein 1;cargo selection protein (mannose 6 phosphate receptor binding protein);MPR-BINDING PROTEIN, 47-KD;placental protein 17;Perilipin-3;47 kDa mannose 6-phosphate receptor-binding protein;47 kDa MPR-binding protein;Cargo selection protein TIP47;Mannose-6-phosphate receptor-binding protein 1;Placental protein 17;perilipin-3;placental protein 17;cargo selection protein TIP47;tail-interacting protein, 47 kD
Recombinant Proteins
- Mouse
- Human
- Cynomolgus
- Mammalian Cell
- E.coli
- HEK293
- Wheat Germ
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- His
- Myc&DDK
- GST
- Non
- His&Fc&Avi
- Flag
Involved Pathway
PLIN3 involved in several pathways and played different roles in them. We selected most pathways PLIN3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PLIN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PLIN3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLIN3 itself. We selected most functions PLIN3 had, and list some proteins which have the same functions with PLIN3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | POLD4,RPS28,PDE2A,ESR2,ROR1,ARSA,PECAM1,ANKRD54,ITGA3,CEACAM6 |
Interacting Protein
PLIN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLIN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLIN3.
q9wmx2-pro_0000037551;CMTM5;RHOBTB3;MAX;TBPL1;SMAD2;q5ngp5_fratt;q7cfv5_yerpe;q81qv1_bacan;ACMSD;wecA;pi3p
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References
- Kimura, A; Sakurai, T; et al. Identification of Target Antigens of Antiendothelial Cell Antibodies Against Human Brain Microvascular Endothelial Cells in Healthy Subjects. CURRENT NEUROVASCULAR RESEARCH 12:25-30(2015).
- Mulay, K; White, VA; et al. Sebaceous carcinoma: clinicopathologic features and diagnostic role of immunohistochemistry (including androgen receptor). CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE 49:326-332(2014).
