PHGDH
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Official Full Name
Phgdh phosphoglycerate dehydrogenase -
Synonyms
PHGDH;phosphoglycerate dehydrogenase;D-3-phosphoglycerate dehydrogenase;3-PGDH;3-phosphoglycerate dehydrogenase;MGC105399
Recombinant Proteins
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- Mammalian Cell
- Sf9 Insect Cell
- HEK293
- E. coli
- Mammalian cells
- HEK293T
- GST
- His
- Flag
- T7
- Non
- N-Twin strep and C-His&Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PHGDH involved in several pathways and played different roles in them. We selected most pathways PHGDH participated on our site, such as Glycine, serine and threonine metabolism,Metabolic pathways,Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PHGDH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | PPCS,DHRS4,PYGL,CYP2P8,ATP5B,CPOX,CYP27A1,TALDO1,ADH2-2,ATP5F1 |
| Glycine, serine and threonine metabolism | DLDH,CBSB,PGAM1A,AGXTB,DAO,ALDH7A1,TDH,GCAT,SRR,GCSH |
| Carbon metabolism | SDHB,PFKMA,PGAM1,PKMA,SDHC,TKTL1,PRPS1A,PDHA1B,GLUD1A,TALDO1 |
| Biosynthesis of amino acids | MTR,ENO1A,OTC,ALDOA,GAPDH,CTH,ASS1,RPIA,PGAM1B,PKMA |
Protein Function
PHGDH has several biochemical functions, for example, NAD binding,electron carrier activity,phosphoglycerate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PHGDH itself. We selected most functions PHGDH had, and list some proteins which have the same functions with PHGDH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| electron carrier activity | FDX1L,NCF1,NCF2,TXNRD1,PTGESL,GPX2,ETFA,SDHD,AIFM1,SDHB |
| NAD binding | LDHB,GPD1L,NNT,SORD,PARP1,IDH1,AHCY,GRHPRA,GPD1C,GLYR1 |
Interacting Protein
PHGDH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PHGDH here. Most of them are supplied by our site. Hope this information will be useful for your research of PHGDH.
Cdk1;TNFRSF1B;Tubb4b;Ddb1;Bles03;MAP3K3;RHOB;MAPK6;PIAS4;TTN;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;15-deoxy-delta(12,14;ere_dna;SLC33A1;GAK;MAPK13;KIF20A
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