PHF7

  • Official Full Name

    PHD finger protein 7

  • Overview

    Spermatogenesis is a complex process regulated by extracellular and intracellular factors as well as cellular interactions among interstitial cells of the testis, Sertoli cells, and germ cells. In the testis, this gene is expressed in Sertoli cells but not germ cells. However, this gene is not expressed in a patient who exhibited spermatogenic arrest at the spermatocyte stage. Spermatogenic arrest is an interruption of germ cell differentiation that may result in oligospermia or azoospermia. The proteins encoded by this gene contain plant homeodomain (PHD) finger domains, also known as leukemia associated protein (LAP) domains, believed to be involved in transcriptional regulation. Thus this protein, which localizes to the nucleus of transfected cells, has been implicated in the transcriptional regulation of spermatogenesis. Two protein isoforms are encoded by transcript variants of this gene.

  • Synonyms

    PHF7;PHD finger protein 7;HSPC226;NYD SP6;testis development protein NYD-SP6;HSPC045;NYD-SP6;MGC26088;DKFZp434L1850

Recombinant Proteins

  • Rhesus macaque
  • Rat
  • Human
  • Mouse
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • His&Fc&Avi
  • Myc&DDK

    Involved Pathway

    PHF7 involved in several pathways and played different roles in them. We selected most pathways PHF7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PHF7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    PHF7 has several biochemical functions, for example, protein binding,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PHF7 itself. We selected most functions PHF7 had, and list some proteins which have the same functions with PHF7. You can find most of the proteins on our site.

    Function Related Protein
    protein binding MAPK7,C10orf62,PTK7,SMAD9,VPS16,AES,GLRX3,SPAG5,PIWIL1,FCHSD2
    zinc ion binding ANKIB1A,KDM2BA,MORC3B,RFFL,CHD4,RFPL2,RNF146,ZDHHC16,WTIP,SPRYD5

    Interacting Protein

    PHF7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PHF7 here. Most of them are supplied by our site. Hope this information will be useful for your research of PHF7.

    UBE2D4;SRPK1;IKBKG;ARIH2;MDM2;TRIM26;RNF111;DTX3L;TRIM41;RNF34;RNF14

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All PHF7 Products

    Required fields are marked with *

    My Review for All PHF7 Products

    Required fields are marked with *