PEX19

  • Official Full Name

    peroxisomal biogenesis factor 19

  • Overview

    This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

  • Synonyms

    PEX19;peroxisomal biogenesis factor 19;peroxisomal farnesylated protein , PXF;D1S2223E;HK33;housekeeping gene;33kD;PMP1;PMPI;PXMP1;peroxin-19;housekeeping gene, 33kD;33 kDa housekeeping protein;peroxisomal farnesylated protein;PXF;FLJ55296

Recombinant Proteins

  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • Mammalian Cell
  • Human
  • HEK293
  • HEK293T
  • GST
  • His
  • Non
  • His&T7
  • Myc&DDK
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
PEX19-1650H Recombinant Human PEX19, GST-tagged E.coli Human GST 1-299aa
PEX19-12650M Recombinant Mouse PEX19 Protein Mammalian Cell Mouse His
PEX19-2318Z Recombinant Zebrafish PEX19 Mammalian Cell Zebrafish His
PEX19-27601TH Recombinant Human PEX19, His-tagged E.coli Human His 296 amino acids
PEX19-28143TH Recombinant Human PEX19, His-tagged E.coli Human His Full L.
PEX19-2962H Recombinant Human PEX19, His-tagged E.coli Human His 1-299 a.a.
PEX19-3637H Recombinant Human PEX19, His-tagged Human Human His
PEX19-3289HCL Recombinant Human PEX19 293 Cell Lysate HEK293 Human Non
Pex19-1693M Recombinant Mouse Pex19 protein, His & T7-tagged E.coli Mouse His&T7 Ala2~Cys296
PEX19-2003H Recombinant Human PEX19 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Human Myc&DDK
Pex19-4798M Recombinant Mouse Pex19 Protein, Myc/DDK-tagged HEK293T Mouse Myc&DDK
PEX19-6647M Recombinant Mouse PEX19 Protein, His (Fc)-Avi-tagged HEK293 Mouse His&Fc&Avi
PEX19-6647M-B Recombinant Mouse PEX19 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    PEX19 involved in several pathways and played different roles in them. We selected most pathways PEX19 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PEX19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Peroxisome PEX6,NOS2B,PEX5L,MLYCD,ACOX1,PEX16,AGXTB,MVK,DDO,ABCD3

    Protein Function

    PEX19 has several biochemical functions, for example, ATPase binding,peroxisome membrane class-1 targeting sequence binding,protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PEX19 itself. We selected most functions PEX19 had, and list some proteins which have the same functions with PEX19. You can find most of the proteins on our site.

    Function Related Protein
    protein N-terminus binding HDAC1,ERCC5,SNF8,TRP53,PARP1,SMARCC1,MYO7A,MEN1,GTF2H2,STXBP1
    ATPase binding SDF2L1,PDE4D,ATPIF1B,SNTA1,ATP6V1G3,FXYD1,DERL1,NOP58,RALB,NR1H2
    protein binding BRCA1,LSM2,YY1,ARL6IP1,CFLAR,MAU2,TERF1,MTMR2,MALSU1,ALCAM

    Interacting Protein

    PEX19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEX19 here. Most of them are supplied by our site. Hope this information will be useful for your research of PEX19.

    PEX3

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