PELP1
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Official Full Name
proline, glutamate and leucine rich protein 1 -
Overview
This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] -
Synonyms
PELP1;proline, glutamate and leucine rich protein 1;MNAR;P160;proline-, glutamic acid- and leucine-rich protein 1;transcription factor HMX3;proline and glutamic acid rich nuclear protein;modulator of non-genomic activity of estrogen receptor
Recombinant Proteins
- Mouse
- Rhesus macaque
- Rat
- Human
- Mammalian Cell
- E. coli
- HEK293
- His
- GST
- His&Fc&Avi
Involved Pathway
PELP1 involved in several pathways and played different roles in them. We selected most pathways PELP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PELP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PELP1 has several biochemical functions, for example, chromatin binding,poly(A) RNA binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PELP1 itself. We selected most functions PELP1 had, and list some proteins which have the same functions with PELP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | CKAP4,RBM12,DDX41,NTPCR,UTP14A,SPTBN1,GRN,ZNF346,STAU2,BOP1 |
| chromatin binding | PHF8,PHC1,MSL1,RAN,TRPS1,SP140,PSIP1,NFKB1,TCF7L2,SSRP1 |
| transcription factor binding | TAF1,GTF2A2,E2F4,HDAC5,TWIST1,ARID5A,HDAC1,PIAS2,PBX2,SIRT2 |
| protein binding | ZFP746,PROC,TDRD9,NLGN4X,PIK3R3,MASP1,USP1,ZFP932,TLE2,ZNHIT6 |
Interacting Protein
PELP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PELP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PELP1.
Nr4a1;Ywhae
Resources
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References
- Dezen, S; Otonel, RAA; et al. Bovine viral diarrhea virus (BVDV) infection profile in a high production dairy herd with vaccination program against BVDV. PESQUISA VETERINARIA BRASILEIRA 33:141-147(2013).
- Antoniassi, NAB; Pavarini, SP; et al. Clinical and pathological changes in sheep naturally infected with bluetongue virus in Rio Grande do Sul, Brazil.. PESQUISA VETERINARIA BRASILEIRA 30:1010-1016(2010).
