PEA15
-
Official Full Name
phosphoprotein enriched in astrocytes 15 -
Overview
PEA-15 is a 15 kDa phosphoprotein expressed abundantly in astrocytes and fibroblasts as well as in tissues, including the lung and eye. The protein has been shown to coordinate cell growth, death, and glucose ultilization. The amino-terminal DED domain of -
Synonyms
PEA15;phosphoprotein enriched in astrocytes 15;astrocytic phosphoprotein PEA-15;HMAT1;homolog of mouse MAT 1 oncogene;HUMMAT1H;MAT1;MAT1H;PEA 15;PED;Phosphoprotein enriched in astrocytes;15kD;homolog of mouse MAT-1 oncogene;phosphoprotein enr
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- His&Fc&Avi
- Flag
- GST
Involved Pathway
PEA15 involved in several pathways and played different roles in them. We selected most pathways PEA15 participated on our site, such as ARMS-mediated activation,Axon guidance,Cytokine Signaling in Immune system, which may be useful for your reference. Also, other proteins which involved in the same pathway with PEA15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine Signaling in Immune system | SOCS3A,RASGRP4,CNKSR1,HBEGF,SPTA1,TRIM10,NRG2A,TRIM45,IFITM2,DUSP6 |
| DAP12 interactions | FGF18B,PEA15A,FGFR1B,SPRED1,SPTB,MARK3,FRS2,JAK1,KLB,ADRBK1 |
| Downstream signal transduction | SPRED2,FGF18B,FRS2A,CNKSR1,MARK3,PAQR3B,AGO1,CRKL,SPTA1,AGO3 |
| Developmental Biology | DAB2IPB,PLXNC1,DOCK1,EFNA1B,EFNB3,KBTBD7,LGI1,HELZ2,ACTR2B,DUSP2 |
| ARMS-mediated activation | PSME3,DLG4,RASGEF1A,DUSP9,CSF2RA,SPTA1,PHB,NRG4,JAK3,CSF2RB |
| Axon guidance | RAC1,SEMA3C,DCC,RNF8,UNC5C,CLTB,ROCK2,EFNB3B,TRPC7,NETO2 |
| DAP12 signaling | PEBP1,AGO2,HBEGF,FGF20A,AGO1,DUSP2,TRAT1,MOV10,FRS2A,FRS3 |
| Downstream signaling of activated FGFR1 | PHB,KBTBD7,SPNA1,AGO2,RASGEF1A,SPRED2,SPTA1,RASGRP4,SPRED1,IL17RD |
Protein Function
PEA15 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PEA15 itself. We selected most functions PEA15 had, and list some proteins which have the same functions with PEA15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CYFIP2,TNNT1,HP1BP3,CDIPT,HNRNPK,SHROOM2,ANXA9,CCNB1IP1,C14orf159,MYLK2 |
Interacting Protein
PEA15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEA15 here. Most of them are supplied by our site. Hope this information will be useful for your research of PEA15.
TERF2IP;MAPK1;ABCD4;PDPK1;MAPK3;L1CAM;AK9;PANK4;LUC7L2;IQCB1
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