PDSS2
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Official Full Name
prenyl (decaprenyl) diphosphate synthase, subunit 2 -
Overview
The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency. -
Synonyms
PDSS2;prenyl (decaprenyl) diphosphate synthase, subunit 2;C6orf210, chromosome 6 open reading frame 210;decaprenyl-diphosphate synthase subunit 2;bA59I9.3;C6orf210;Candidate tumor suppressor protein;chromosome 6 open reading frame 210;decaprenyl pyrophosphate synthetase subunit 2;DLP1;hDLP1;subunit 2 of decaprenyl diphosphate synthase;decaprenyl pyrophosphate synthase subunit 2;all-trans-decaprenyl-diphosphate synthase subunit 2
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PDSS2 involved in several pathways and played different roles in them. We selected most pathways PDSS2 participated on our site, such as Terpenoid backbone biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDSS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Terpenoid backbone biosynthesis | ICMT,PMVK,PDSS1,PCYOX1,ZMPSTE24,HMGCRA,HMGCS1,IDI2,GGPS1,DHDDS |
Protein Function
PDSS2 has several biochemical functions, for example, protein heterodimerization activity,contributes_to trans-hexaprenyltranstransferase activity,trans-octaprenyltranstransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDSS2 itself. We selected most functions PDSS2 had, and list some proteins which have the same functions with PDSS2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| contributes_to trans-hexaprenyltranstransferase activity | PDSS1 |
| protein heterodimerization activity | HIST1H2BM,ROPN1B,TXLNG,TAP1,BAD,YWHAE,UBA2,KATNA1,BOKA,NKX2-5 |
Interacting Protein
PDSS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDSS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDSS2.
ispB
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