PCBP1
-
Official Full Name
poly(rC) binding protein 1 -
Synonyms
PCBP1;poly(rC) binding protein 1;poly(rC)-binding protein 1;heterogeneous nuclear ribonucleoprotein E1;hnRNP E1;hnRNP X;HNRPE1;HNRPX;alpha-CP1;nucleic acid-binding protein SUB2.3;heterogenous nuclear ribonucleoprotein X;heterogenous nuclear ribonucleoprotein E1;hnRNP-X;hnRNP-E1
Recombinant Proteins
- Mouse
- Human
- Pig
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- Mamanlian cells
- His
- His&Fc
- Myc&DDK
- Non
- Flag
- His&Fc&Avi
Involved Pathway
PCBP1 involved in several pathways and played different roles in them. We selected most pathways PCBP1 participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PCBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Spliceosome | SNRPF,SNRPA,EIF4A3,PUF60,SNRPD2,SRSF7,PUF60A,CDC5L,SF3B6,WBP11 |
Protein Function
PCBP1 has several biochemical functions, for example, RNA binding,mRNA binding,poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCBP1 itself. We selected most functions PCBP1 had, and list some proteins which have the same functions with PCBP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | DZIP3,RPL21,RNASET2,EIF4H,CNOT6,DHX34,PKZ,PABPC1A,SF1,TLR13 |
| mRNA binding | THOC2,RC3H2,KIAA0020,SLBP,LIN28A,PIWIL2,RBM4,CROP,NANOS2,QKI |
| protein binding | WDR11,SPANXC,APOA4,MRPL45,TMEM199,CD8B1,PAGE5,ACAD9,PAK3,C3orf62 |
| poly(A) RNA binding | RPL19,MTERF,CPEB3,PEG10,KIAA0020,ELAC2,UPF1,SCG3,EXOSC6,DDX41 |
| single-stranded DNA binding | HMGB1,SUB1,TDP1,MCM6,RAD23A,RBMS1,ANXA1,XRCC3,HNRNPDL,ERCC5 |
Interacting Protein
PCBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCBP1.
GAMMAHV.ORF34;SNRPA;THAP11;PABPC1;q12771_human;PTBP1;PPIG;PCBP2
Resources
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References
- Nahar-Gohad, P; Sultan, H; et al. RACK1 identified as the PCBP1-interacting protein with a novel functional role on the regulation of human MOR gene expression. JOURNAL OF NEUROCHEMISTRY 124:466-477(2013).
- Sean, P; Nguyen, JHC; et al. The linker domain of poly(rC) binding protein 2 is a major determinant in poliovirus cap-independent translation. VIROLOGY 378:243-253(2008).
