PARVA
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Official Full Name
parvin, alpha -
Overview
This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival. -
Synonyms
PARVA;parvin, alpha;matrix remodelling associated 2 , MXRA2;alpha-parvin;FLJ10793;FLJ12254;Actopaxin;Alpha parvin;Calponin like integrin linked kinase binding protein;CH ILKBP;Matrix remodelling associated 2;Matrix remodelling associated protein 2;MXRA 2;MXRA2;PARV A;matrix-remodeling-associated protein 2;calponin-like integrin-linked kinase-binding protein;CH-ILKBP
Recombinant Proteins
- Mouse
- Human
- Rat
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- His
- GST
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PARVA involved in several pathways and played different roles in them. We selected most pathways PARVA participated on our site, such as Focal adhesion, which may be useful for your reference. Also, other proteins which involved in the same pathway with PARVA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Focal adhesion | VAV3B,MYL9,MYL7,LAMB2,PDGFA,MYL9A,ACTB2,CDC42,GRB2,PRKCBB |
Protein Function
PARVA has several biochemical functions, for example, actin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PARVA itself. We selected most functions PARVA had, and list some proteins which have the same functions with PARVA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | SPTBN2,CALD1,ABLIM1,MYHC4,SMYHC2,WASF3,LIMCH1,DIAP3,MED28,ABLIM1A |
| protein binding | HEXIM1,MED18,HBA1,ARFGAP1,ZBTB4,SERPINF1,ZFYVE1,HSD17B12,NPDC1,CAPN3 |
Interacting Protein
PARVA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PARVA here. Most of them are supplied by our site. Hope this information will be useful for your research of PARVA.
ILK;MOCOS;7705955;PXN;DHX36
Resources
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References
- Eygelaar, D; Jori, F; et al. Tick-borne haemoparasites in African buffalo (Syncerus caffer) from two wildlife areas in Northern Botswana. PARASITES & VECTORS 8:-(2015).
- Wesonga, FD; Gachohi, JM; et al. Theileria parva infection seroprevalence and associated risk factors in cattle in Machakos County, Kenya. TROPICAL ANIMAL HEALTH AND PRODUCTION 47:93-101(2015).
