PARD6B
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Official Full Name
par-6 partitioning defective 6 homolog beta (C. elegans) -
Overview
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. -
Synonyms
PARD6B;par-6 partitioning defective 6 homolog beta (C. elegans);par 6 (partitioning defective 6, C.elegans) homolog beta;partitioning defective 6 homolog beta;PAR 6B;PAR 6 beta;Par 6 partitioning defective 6 homolog beta (C. elegans);PAR6B;PARD6 beta;PAR-6 beta;OTTHUMP00000031269
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PARD6B-1527H | Recombinant Human PARD6B, His-tagged | E.coli | Human | His | 1-372aa |
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| PARD6B-12359M | Recombinant Mouse PARD6B Protein | Mammalian Cell | Mouse | His |
|
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| PARD6B-3433C | Recombinant Chicken PARD6B | Mammalian Cell | Chicken | His |
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| PARD6B-5949Z | Recombinant Zebrafish PARD6B | Mammalian Cell | Zebrafish | His |
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| PARD6B-7058H | Recombinant Human PARD6B, His-tagged | E.coli | Human | His | 1-372aa |
|
| PARD6B-3435HCL | Recombinant Human PARD6B 293 Cell Lysate | HEK293 | Human | Non |
|
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| PARD6B-6496M | Recombinant Mouse PARD6B Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PARD6B-6496M-B | Recombinant Mouse PARD6B Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PARD6B involved in several pathways and played different roles in them. We selected most pathways PARD6B participated on our site, such as Rap signaling pathway,Endocytosis,Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PARD6B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Rap signaling pathway | RRAS,Itgam&Itgb2,FGF10,GNAO1,PARD6A,FGFR3,CALML3,HGF,PFN2,MLLT4 |
| Endocytosis | ARAP3,TSG101A,PIP5K1A,ADRB3B,DDL-2,PIP5K1BB,GRK1B,RET,RAB8A,CCDC53 |
| Tight junction | CLDN23,CLDN2,EPB41,MYL10,JAM2,CTTN,OCLNB,ACTB1,SPTAN1,PRKCG |
| Hippo signaling pathway | ITGB2,FZD8,RASSF1,PPP2R1A,FRMD6,TEAD4,YWHAE,MOB1A,FZD6,PPP1CA |
Protein Function
PARD6B has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PARD6B itself. We selected most functions PARD6B had, and list some proteins which have the same functions with PARD6B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ZNF232,CD93,CDC16,NOP56,BRK1,NLRP3,DHX32,TFDP2,SIX3,MEIOB |
Interacting Protein
PARD6B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PARD6B here. Most of them are supplied by our site. Hope this information will be useful for your research of PARD6B.
CDC42;PRKCI
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References
- Chen, J; Xu, ZY; et al. Association between DNA methylation and multidrug resistance in human glioma SHG-44 cells. MOLECULAR MEDICINE REPORTS 11:43-52(2015).
- Kono, K; Tamashiro, DAA; et al. Inhibition of RHO-ROCK signaling enhances ICM and suppresses TE characteristics through activation of Hippo signaling in the mouse blastocyst. DEVELOPMENTAL BIOLOGY 394:142-155(2014).
