PAFAH1B2
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Official Full Name
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) -
Overview
Platelet-activating factor acetylhydrolase (PAFAH) inactivates platelet-activating factor (PAF) into acetate and;LYSO-PAF. This gene encodes the beta subunit of PAFAH, the other subunits are alpha and gamma. Multiple alternatively;spliced transcript variants that encode different protein isoforms have been described for this gene. -
Synonyms
PAFAH1B2;platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa);platelet-activating factor acetylhydrolase IB subunit beta;PAF acetylhydrolase 30 kDa subunit;PAF AH 30 kDa subunit;PAF AH beta subunit;PAF AH subunit beta;PAFAH 30 kDa subunit;PAFAH beta subunit;PAFAH subunit beta;PAFAH1B2 protein;PAFAHB;Platelet activating factor acetylhydrolase IB beta subunit;Platelet activating factor acetylhydrolase IB subunit beta;Platelet activating factor acetylhydrolase isoform Ib beta subunit;PAF-AH subunit beta;PAF-AH 30 kDa subunit;platelet-activating factor acetylhydrolase, isoform Ib, subunit 2 (30kDa);platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa;platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD)
Recombinant Proteins
- Mouse
- Chicken
- Human
- Rhesus macaque
- Rat
- Zebrafish
- Mammalian Cell
- E.coli
- HEK293
- Mammalian cells
- HEK293T
- His
- Non
- GST
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
PAFAH1B2 involved in several pathways and played different roles in them. We selected most pathways PAFAH1B2 participated on our site, such as Ether lipid metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PAFAH1B2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | GSTZ1,COX6A1,ACAA2,TCIRG1,GPT2,ATP6V0D2,MCCC1,IPPK,COX8C,PAFAH2 |
| Ether lipid metabolism | PLA2G3,PLA2G5,ENPP2,PPAP2C,PAFAH1B3,CEPT1,PLD4,PLD2,PAFAH1B1B,PLA2G4AA |
Protein Function
PAFAH1B2 has several biochemical functions, for example, 1-alkyl-2-acetylglycerophosphocholine esterase activity,platelet-activating factor acetyltransferase activity,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PAFAH1B2 itself. We selected most functions PAFAH1B2 had, and list some proteins which have the same functions with PAFAH1B2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 1-alkyl-2-acetylglycerophosphocholine esterase activity | PAFAH1B3,PAFAH2,ASPG,PLA2G7 |
| protein homodimerization activity | TFAP2E,FOXP2,PRLR,LILRB1,PVRL4,PEX7,SLC11A1,CER1,SYT10,TENM2 |
| protein heterodimerization activity | TAS1R1,EPAS1,TYRO3,IRAK2,TIMELESS,BARD1,SPTA1,HOMER1,HIST2H4A,NFYC |
| platelet-activating factor acetyltransferase activity | PAFAH1B3 |
Interacting Protein
PAFAH1B2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAFAH1B2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAFAH1B2.
Pafah1b1;CRK;EPB41;NME2;MCC;MPG;PRKAB1;TRAF6;PARK2;SNUPN;RPLP0;STAT3;CCT3;ZFP36L1;SLA;PAFAH1B3;TIMM50;REXO1
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References
- Salaverria, I; Martin-Guerrero, I; et al. A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma. BLOOD 123:1187-1198(2014).
- Peloso, GM; Auer, PL; et al. Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks. AMERICAN JOURNAL OF HUMAN GENETICS 94:223-232(2014).
