OSBPL2
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Official Full Name
oxysterol binding protein-like 2 -
Overview
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. -
Synonyms
OSBPL2;oxysterol binding protein-like 2;oxysterol binding protein like 2;oxysterol-binding protein-related protein 2;KIAA0772;ORP 2;OSBP-related protein 2;oxysterol-binding protein-like 2;ORP2;ORP-2;MGC4307;MGC8342;FLJ20223
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OSBPL2-1469H | Recombinant Human OSBPL2, His-tagged | E.coli | Human | His | 128-480aa | |
| OSBPL2-1827C | Recombinant Chicken OSBPL2 | Mammalian Cell | Chicken | His |
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| OSBPL2-3538HCL | Recombinant Human OSBPL2 293 Cell Lysate | HEK293 | Human | Non |
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| OSBPL2-3516H | Recombinant Human OSBPL2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| OSBPL2-4605H | Recombinant Human OSBPL2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Osbpl2-4609M | Recombinant Mouse Osbpl2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
OSBPL2 involved in several pathways and played different roles in them. We selected most pathways OSBPL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OSBPL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
OSBPL2 has several biochemical functions, for example, cholesterol binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OSBPL2 itself. We selected most functions OSBPL2 had, and list some proteins which have the same functions with OSBPL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CFL1,CRIPAK,KDRL,GSTO2,NLRC5,MAP3K9,ZNF524,BIRC3,EGR2,SRPX2 |
| cholesterol binding | APOA4A,APOE,OSBPL7,ERLIN2,OSBPL1A,NPC2,NR1H3,SOAT1,STARD3,OSBPL5 |
Interacting Protein
OSBPL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OSBPL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of OSBPL2.
VAPB;thiF
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