Nphp3
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Official Full Name
nephronophthisis 3 (adolescent)
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NPHP3-1342H | Recombinant Human NPHP3, His-tagged | E.coli | Human | His | 1-131aa | |
| NPHP3-1809H | Recombinant Human NPHP3 protein, GST-tagged | E.coli | Human | GST | 1-131 aa | |
| NPHP3-10820M | Recombinant Mouse NPHP3 Protein | Mammalian Cell | Mouse | His |
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| NPHP3-7969Z | Recombinant Zebrafish NPHP3 | Mammalian Cell | Zebrafish | His |
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| NPHP3-869H | Recombinant Human NPHP3 | Mammalian Cell | Human | His |
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| NPHP3-3663H | Recombinant Human NPHP3 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| NPHP3-3663H-B | Recombinant Human NPHP3 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| NPHP3-6028H | Recombinant Human NPHP3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| NPHP3-6158M | Recombinant Mouse NPHP3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NPHP3-6158M-B | Recombinant Mouse NPHP3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Nphp3 involved in several pathways and played different roles in them. We selected most pathways Nphp3 participated on our site, such as Assembly of the primary cilium,Cargo trafficking to the periciliary membrane,Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with Nphp3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Organelle biogenesis and maintenance | TMEM216,BBS1,KIF3CB,MRPL44,AURKAIP1,MRPL52,IFT88,MRPL47,DAP3,IQCB1 |
| Assembly of the primary cilium | CEP78,CETN2,UNC119.1,TTC30A2,TTC30B,NEDD1,CCT5,MKS1,BBS7,IFT20 |
| Cargo trafficking to the periciliary membrane | TCP1,CCT8,TTC8,BBS4,CCT2,BBS12,ARL13B,EXOC5,CYS1,RAB3IP |
| Trafficking of myristoylated proteins to the cilium | CYS1,RP2,ARL3,UNC119B,UNC119.1 |
Protein Function
Nphp3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Nphp3 itself. We selected most functions Nphp3 had, and list some proteins which have the same functions with Nphp3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | IRF2BP1,CEBPA,NAMPT,ZFP335,KRTAP10-4,POLR3F,PIDD1,XRCC6,GJB6,PDCL |
Interacting Protein
Nphp3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Nphp3 here. Most of them are supplied by our site. Hope this information will be useful for your research of Nphp3.
UNC119B;UNC119;CEP164;DYSF;ATXN1;q5new4_fratt;Ncapg2;Uso1
Resources
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References
- Leeman, KT; Dobson, L; et al. NPHP3 mutations are associated with neonatal onset multiorgan polycystic disease in two siblings. JOURNAL OF PERINATOLOGY 34:410-411(2014).
- Fiskerstrand, T; Houge, G; et al. Identification of a Gene for Renal-Hepatic-Pancreatic Dysplasia by Microarray-Based Homozygosity Mapping. JOURNAL OF MOLECULAR DIAGNOSTICS 12:125-131(2010).
