NUP98
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Official Full Name
NUP98 nucleoporin 98kDa -
Overview
Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC). This protein plays a critical role in nuclear trafficking. Nup98 plays a specific role in the RNA export. -
Synonyms
NUP98;nucleoporin 98kDa;nucleoporin 98kD;nuclear pore complex protein Nup98-Nup96;NUP96;Nup98-Nup96;GLFG-repeat containing nucleoporin;ADIR2;NUP196
Recombinant Proteins
- Zebrafish
- Human
- Mouse
- Mammalian Cell
- E.coli
- Mammalian cell
- HEK293
- His
- His&T7
- Non
- His&GST
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NUP98-10953Z | Recombinant Zebrafish NUP98 | Mammalian Cell | Zebrafish | His |
|
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| NUP98-5792H | Recombinant Human NUP98 protein, His-tagged | E.coli | Human | His | Gln629~Pro894 |
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| Nup98-5793M | Recombinant Mouse Nup98 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Thr568~Tyr776 |
|
| NUP98-1235HCL | Recombinant Human NUP98 cell lysate | Human | Non |
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| NUP98-3235M | Recombinant Mouse NUP98 protein, His-GST-tagged | E.coli | Mouse | His&GST | Thr568~Tyr776 |
|
| NUP98-4443H | Recombinant Human NUP98 protein, hFc-tagged | Mammalian cell | Human | Fc | 1-880aa |
|
| NUP98-5793H | Recombinant Human NUP98 protein, hFC-tagged | HEK293 | Human | Fc | Partial |
|
Involved Pathway
NUP98 involved in several pathways and played different roles in them. We selected most pathways NUP98 participated on our site, such as RNA transport,Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUP98 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Influenza A | IFN-a,IFNA1,IL33,IFNA21,PLG,NXT2,IFNA5,KPNA1,TNFSF10,MAPK12 |
| RNA transport | NUP107,EIF3E,SUMO2,NCBP2,CASC3,PABPC1A,XPO1,GEMIN2,SRRM1,EIF5 |
Protein Function
NUP98 has several biochemical functions, for example, peptide binding,protein binding,structural constituent of nuclear pore. Some of the functions are cooperated with other proteins, some of the functions could acted by NUP98 itself. We selected most functions NUP98 had, and list some proteins which have the same functions with NUP98. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| peptide binding | NLN,NPFFR2,MME,ERCC3,GNRHR,NPFFR1L2,CSNK1D,FURIN,OXTRL,CMA1 |
| protein binding | EPB41,KRT6A,RPS19BP1,C2orf28,UQCC1,DAK,GATC,GAB1,STIM1,SNAP47 |
| structural constituent of nuclear pore | TMEM33,NUP54,NDC1,NUP153,NUP85,NUP107,NUP62CL,NUP205,NUP62L,NUP62 |
| transporter activity | AQP9B,PTGDSA,SLC22A13,SLC5A9,SLC37A4B,SLCO1A5,RASSF9,ATP6AP1,SLCO1A4,FABP7B |
Interacting Protein
NUP98 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUP98 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUP98.
NXF1;Nup107;hin1l_human;gag-pol;CHM;Nup98;Nup188;Nup214;USP7;HNRNPUL1;QRICH2;MOB1A;APC;uxaC;npm_alk;E2F3;MYC;M
Resources
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References
- Chatel, G; Desai, SH; et al. Domain topology of nucleoporin Nup98 within the nuclear pore complex. JOURNAL OF STRUCTURAL BIOLOGY 177:81-89(2012).
- Puthiyaveetil, AG; Heid, B; et al. A NUP98-HOXD13 leukemic fusion gene leads to impaired class switch recombination and antibody production. EXPERIMENTAL HEMATOLOGY 40:622-633(2012).
