NRL
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Official Full Name
neural retina leucine zipper -
Overview
This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases. -
Synonyms
NRL;neural retina leucine zipper;neural retina-specific leucine zipper protein;D14S46E;NRL MAF;RP27;Neural retinal specific leucine zipper;NRL_HUMAN;neural retinal-specific leucine zipper;NRL-MAF
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- Non
- His&Myc&SUMO
- His&Myc
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NRL-1368H | Recombinant Human NRL, GST-tagged | E.coli | Human | GST | 1-237aa | |
| NRL-10894M | Recombinant Mouse NRL Protein | Mammalian Cell | Mouse | His |
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| NRL-293H | Recombinant Human NRL | Mammalian Cell | Human | His |
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| NRL-3762Z | Recombinant Zebrafish NRL | Mammalian Cell | Zebrafish | His |
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| NRL-749H | Recombinant Human NRL Protein, His-tagged | E.coli | Human | His |
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| NRL-3693HCL | Recombinant Human NRL 293 Cell Lysate | HEK293 | Human | Non |
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| NRL-2535M | Recombinant Mouse NRL Protein (1-237 aa), His-SUMO-Myc-tagged | E.coli | Mouse | His&Myc&SUMO | 1-237 aa |
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| NRL-3293H | Recombinant Human NRL protein, His&Myc-tagged | E.coli | Human | His&Myc | 1-237aa |
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| NRL-3683H | Recombinant Human NRL Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| NRL-3683H-B | Recombinant Human NRL Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| NRL-6206M | Recombinant Mouse NRL Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NRL-6206M-B | Recombinant Mouse NRL Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
NRL involved in several pathways and played different roles in them. We selected most pathways NRL participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NRL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NRL has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,leucine zipper domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NRL itself. We selected most functions NRL had, and list some proteins which have the same functions with NRL. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZNF224,MYEF2,PML,MBD1,MAFGB,ZNF507,TBX4,PRM1,ZFP667,ZBTB25 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | CREB3L2,TTC6,OTX2,TCF12,NKX6-2,AEBP2,JUNBB,PATZ1,POU4F3,HINFP |
| leucine zipper domain binding | CRX,PAWR,MKL1,DDIT3,DAPK3,ERC1,PMF1,AATF,ATF4,KCNA3 |
| protein binding | EGLN2,WBP2NL,RPAP3,SLC30A1,PADI4,FRMPD1,PRMT8,PIK3R2,ZNF581,SULT1A2 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | ZIC3,NR4A3,ZNF750,NFKB2,MAFB,DDIT3,FIGLA,GMEB1,FOS,GATA1 |
Interacting Protein
NRL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRL here. Most of them are supplied by our site. Hope this information will be useful for your research of NRL.
CRX;Rax
Resources
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References
- Wang, CX; Hosono, K; et al. Interaction between optineurin and the bZIP transcription factor NRL. CELL BIOLOGY INTERNATIONAL 38:16-25(2014).
- von der Gathen, Y; Sander, I; et al. Quantification of protein and latex allergen content of various natural rubber latex products. ALLERGOLOGIE 35:310-322(2012).
