NRD1
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Official Full Name
nardilysin (N-arginine dibasic convertase) -
Overview
This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011] -
Synonyms
NRD1;nardilysin (N-arginine dibasic convertase);hNRD1;hNRD2;nardilysin;NRD-C;NRD convertase
Recombinant Proteins
- Human
- Chicken
- Rat
- Mouse
- HEK293
- Wheat Germ
- Mammalian Cell
- E.coli
- HEK293T
- Mamanlian cells
- Myc&DDK
- GST
- His
- His&Fc&Avi
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NRD1-185H | Recombinant Human NRD1 protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| NRD1-186H | Recombinant Human NRD1 protein, GST-tagged | Wheat Germ | Human | GST | 1058-1156 a.a. |
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| NRD1-2940C | Recombinant Chicken NRD1 | Mammalian Cell | Chicken | His |
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| NRD1-4078R | Recombinant Rat NRD1 Protein | Mammalian Cell | Rat | His |
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| Nrd1-1859M | Recombinant Mouse Nrd1 Protein, His-tagged | E.coli | Mouse | His | Tyr834-Lys1161 |
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| NRD1-2509H | Recombinant Human NRD1 Protein, His-tagged | E.coli | Human | His | Ala823-Lys1150 |
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| NRD1-3737R | Recombinant Rat NRD1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| NRD1-3737R-B | Recombinant Rat NRD1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Nrd1-4498M | Recombinant Mouse Nrd1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| NRD1-9019HFL | Recombinant Full Length Human NRD1 protein, Flag-tagged | Mamanlian cells | Human | Flag | Full L. |
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Involved Pathway
NRD1 involved in several pathways and played different roles in them. We selected most pathways NRD1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NRD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
NRD1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by NRD1 itself. We selected most functions NRD1 had, and list some proteins which have the same functions with NRD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
NRD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NRD1.
Resources
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References
- Ishizu-Higashi, S; Seno, H; et al. Deletion of Nardilysin Prevents the Development of Steatohepatitis and Liver Fibrotic Changes. PLOS ONE 9:-(2014).
- Ohno, M; Hiraoka, Y; et al. Nardilysin prevents amyloid plaque formation by enhancing alpha-secretase activity in an Alzheimer's disease mouse model. NEUROBIOLOGY OF AGING 35:213-222(2014).
