NPSR1

  • Official Full Name

    neuropeptide S receptor 1

  • Overview

    This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Mutations in this gene have also been associated with this disease. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

  • Synonyms

    NPSR1;neuropeptide S receptor 1;GPRA;NPSR;VRR1;ASRT2;PGR14;GPR154;neuropeptide S receptor;G protein-coupled receptor 154;G-protein coupled receptor 154;G-protein coupled receptor PGR14;G protein-coupled receptor for asthma susceptibility;G-protein coupled receptor for asthma susceptibility

Recombinant Proteins

  • Human
  • Rhesus macaque
  • Rat
  • Macaca mulatta
  • Mus musculus
  • E.coli
  • Mammalian Cell
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • E.coli expression system
  • GST
  • His
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
NPSR1-1348H Recombinant Human NPSR1, GST-tagged E.coli Human GST 1-52aa
NPSR1-3082R Recombinant Rhesus monkey NPSR1 Protein, His-tagged Mammalian Cell Rhesus macaque His
NPSR1-3728HCL Recombinant Human NPSR1 293 Cell Lysate HEK293 Human Non
NPSR1-2901R Recombinant Rhesus Macaque NPSR1 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque His&Fc&Avi
NPSR1-2901R-B Recombinant Rhesus Macaque NPSR1 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
NPSR1-5196H Recombinant Human NPSR1 Protein, GST-tagged Wheat Germ Human GST
NPSR1-6047H Recombinant Human NPSR1 Protein Wheat Germ Human Non
NPSR1-6648HF Recombinant Full Length Human NPSR1 Protein In Vitro Cell Free System Human Full L. 224 amino acids
RFL14224RF Recombinant Full Length Rat Neuropeptide S Receptor(Npsr1) Protein, His-Tagged E.coli expression system Rat His Full L. Full Length (1-372)
RFL22148HF Recombinant Full Length Human Neuropeptide S Receptor(Npsr1) Protein, His-Tagged E.coli expression system Human His Full L. Full Length (1-371)
RFL32172MF Recombinant Full Length Macaca Mulatta Neuropeptide S Receptor(Npsr1) Protein, His-Tagged E.coli expression system Macaca mulatta His Full L. Full Length (1-371)
RFL36747MF Recombinant Full Length Mouse Neuropeptide S Receptor(Npsr1) Protein, His-Tagged E.coli expression system Mus musculus His Full L. Full Length (1-371)

    Involved Pathway

    NPSR1 involved in several pathways and played different roles in them. We selected most pathways NPSR1 participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (q) signalling events,G alpha (s) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with NPSR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Peptide ligand-binding receptors PENKB,CCRL2,APLNR,INSL3,NMBB,QRFP,QRFPR,EDN3,RXFP2,HCRT
    G alpha (s) signalling events CRHB,CRHR2,ADM2A,GCGA,ADRB3,PTHLH,CALCA,PTHRP2,RAMP3,DRD5
    GPCR downstream signaling HEBP1,TAC3,KALRN,ARHGEF1A,RGS11,NMBA,ARHGEF9,ADRA2A,SCT,GPR65
    Class A/1 (Rhodopsin-like receptors) UTS2,SAA1,NPFF,ADORA1,NMB,ADRA1B,AGT,RGR,PROKR1A,RXFP2
    G alpha (q) signalling events GPR4,EDN3,TRPC7,PRKCHB,QRFP,GPRC6A,OPN4,ANXA1B,NMBA,CCK
    GPCR ligand binding SSTR1,SCT,CX3CR1,SST,GRP,PTHLH,NPFFR2,ADORA3,SSTR3,GPR31
    Gastrin-CREB signalling pathway via PKC and MAPK OXTRL,LPAR2B,NPS,DGKG,RGS19,UTS2D,GCGB,QRFP,NMB,PROKR1
    Signal Transduction HCRT,TAS2R3,KIF7,GPR77,ACVR1C,HEYL,ADCYAP1B,FAM13B,ACKR4,RHOV

    Protein Function

    NPSR1 has several biochemical functions, for example, neuropeptide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NPSR1 itself. We selected most functions NPSR1 had, and list some proteins which have the same functions with NPSR1. You can find most of the proteins on our site.

    Function Related Protein
    neuropeptide receptor activity GPR139,KISS1RB,NPFFR2,NPFFR1L2,NPFFR1L1,SORCS2,NMUR1,MCHR1,NPFFR2.1,PRLHR

    Interacting Protein

    NPSR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPSR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NPSR1.

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