NPPC
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Official Full Name
natriuretic peptide C -
Overview
pro C-type natriuretic peptide (proCNP) has vasorelaxant activity and cGMP stimulating activity. It belongs to the natriuretic peptide family. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control. -
Synonyms
NPPC;natriuretic peptide C;natriuretic peptide precursor C;C-type natriuretic peptide;CNP;CNP2
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- His
- His&GST
- His&Fc&Avi
Involved Pathway
NPPC involved in several pathways and played different roles in them. We selected most pathways NPPC participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NPPC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NPPC has several biochemical functions, for example, hormone activity,peptide hormone receptor binding,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NPPC itself. We selected most functions NPPC had, and list some proteins which have the same functions with NPPC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hormone activity | EDN1,GCGA,CRHB,PTH1A,CCK,RETN,STC1,PRL2C3,GPHA2,UCN2 |
| peptide hormone receptor binding | FYN,PTH,ADCYAP1,JAK2,LEP,RUNDC3A,PTHLH,PTHLHA,PTPN11,NPPA |
| protein homodimerization activity | TIMELESS,TOX3,ANO2,DMRT2A,MGLL,HLCS,WHRN,ODC1,ODZ4,DMRTC2 |
| receptor binding | RAB8B,NTF3,NCR3,CNTFR,RCHY1,POU2F1,Ifnl2,DRD1A,JAK2,GIPC1 |
Interacting Protein
NPPC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPPC here. Most of them are supplied by our site. Hope this information will be useful for your research of NPPC.
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References
- Blaha, M; Nemcova, L; et al. Cyclic guanosine monophosphate does not inhibit gonadotropin-induced activation of mitogen-activated protein kinase 3/1 in pig cumulus-oocyte complexes. REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY 13:-(2015).
- Goswami, SC; Thierry-Mieg, D; et al. Itch-associated peptides: RNA-Seq and bioinformatic analysis of natriuretic precursor peptide B and gastrin releasing peptide in dorsal root and trigeminal ganglia, and the spinal cord. MOLECULAR PAIN 10:-(2014).
