NPFF
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Official Full Name
neuropeptide FF-amide peptide precursor -
Synonyms
NPFF;neuropeptide FF-amide peptide precursor;FMRFamide-related peptides;FMFRamide related peptide precursor;FMRFAL;FMRFamide related peptides precursor;FMRFamide-related peptides [Precursor];Neuropeptide FF amide peptide precursor;NPFF protein
Recombinant Proteins
- Mouse
- Rat
- Human
- E.coli
- Mammalian Cell
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His&GST
- His
- Non
- His&Fc&Avi
- GST
Involved Pathway
NPFF involved in several pathways and played different roles in them. We selected most pathways NPFF participated on our site, such as Class A/1 (Rhodopsin-like receptors),G alpha (q) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with NPFF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Peptide ligand-binding receptors | NMBA,PROKR1,APLNR,EDN2,CCL19A.2,PENK,SSTR1,RXFP2,PROKR1A,CCL35.1 |
| Class A/1 (Rhodopsin-like receptors) | ADORA3,EDN2,QRFP,PROKR1,CCR5,PNOC,PENKB,HCRT,CCR3,CCR6 |
| Orexin and neuropeptides FF and QRFP bind to their respective receptors | QRFPR,NPFFR2,HCRT,QRFP |
| GPCR ligand binding | EMR3,LPAR5A,NTS,EDN3,EDNRA,NMU,GPR120,PROKR1,GRP,CRH |
| GPCR downstream signaling | RLN2,GPR17,ANXA1A,FGD4,APPB,HCAR1-2,TAS2R16,RGS10,SST,ADRA2C |
| Gastrin-CREB signalling pathway via PKC and MAPK | EDN1,LPAR1,NPSR1,KISS1,GPR4,OXTRL,ABHD12,GPR65,PMCH,NMBB |
| G alpha (q) signalling events | NPSR1,CASR,NMU,AGTR1,OPN4A,NTS,CYSLTR1,ABHD6B,EDNRAB,EDNRA |
| Signal Transduction | ABI1A,RNF41,ARHGEF16,DHRS4,RNF146,RDH14B,ARHGAP17A,TAS2R3,HECW1,CSN2 |
Protein Function
NPFF has several biochemical functions, for example, G-protein coupled receptor binding,neuropeptide hormone activity,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NPFF itself. We selected most functions NPFF had, and list some proteins which have the same functions with NPFF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor binding | UCN2,ARRB2,GNAI2A,PACRG,PROK1,SAA1,PSAPL1,CORT,PROK2,GNA15.4 |
| receptor binding | MPV17L,LTB,IL29,AGRP,MLYCD,TRIM24,SERPINE2,HIST2H3C2,IFNL3,ALCAM |
| neuropeptide hormone activity | C12orf39,NPFFL,GRP,NTS,HCRT,CALCB,CRH,PYY,PRLH,PNOC |
Interacting Protein
NPFF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPFF here. Most of them are supplied by our site. Hope this information will be useful for your research of NPFF.
ZDHHC17
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References
- Narita, K; Takeda, S; et al. Cilia in the choroid plexus: their roles in hydrocephalus and beyond. FRONTIERS IN CELLULAR NEUROSCIENCE 9:-(2015).
- Sun, YL; Chen, XH; et al. Neuropeptide FF attenuates RANKL-induced differentiation of macrophage-like cells into osteoclast-like cells. ARCHIVES OF ORAL BIOLOGY 60:282-292(2015).
