NMT2
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Official Full Name
N-myristoyltransferase 2 -
Overview
N-myristoyltransferase (NMT) catalyzes the reaction of N-terminal myristoylation of many signaling proteins. It;transfers myristic acid from myristoyl coenzyme A to the amino group of a proteins N-terminal glycine residue.;Biochemical evidence indicates the presence of several distinct NMTs, varying in apparent molecular weight and /or;subcellular distribution. The predicted 498-amino acid of human NMT2 protein shares 77% and 96% sequence identity with;human NMT1 and mouse Nmt2 comprise two distinct families of N-myristoyltransferases. -
Synonyms
NMT2;N-myristoyltransferase 2;glycylpeptide N-tetradecanoyltransferase 2;NMT 2;type II N-myristoyltransferase;peptide N-myristoyltransferase 2;myristoyl-CoA:protein N-myristoyltransferase 2
Recombinant Proteins
- Mouse
- Human
- Zebrafish
- Mammalian Cell
- Wheat Germ
- E.coli
- HEK293
- Mammalian cells
- HEK293T
- In Vitro Cell Free System
- His
- GST
- T7
- Non
- His&Fc&Avi
- Flag
- Myc&DDK
Involved Pathway
NMT2 involved in several pathways and played different roles in them. We selected most pathways NMT2 participated on our site, such as Assembly Of The HIV Virion,Disease,HIV Infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with NMT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| HIV Life Cycle | PSTPIP2,CHMP4C,NMT1,RCC1,ELL,TAF1L,CHMP4B,PSIP1,TCEB3,SSRP1 |
| Late Phase of HIV Life Cycle | TAF1L,RCC1,PDCD6IP |
| Disease | HEYL,SFTPB,AP2M1,OS9,ANTXR1,CTBP1,DPF1,AP2S1,TAF1L,RPL35 |
| Inactivation, recovery and regulation of the phototransduction cascade | METAP1,NMT1,PPEF1,GRK7,CNGA1,METAP2B,RGS9BP,RLN1,RHOL,GNB5A |
| Assembly Of The HIV Virion | VPS37A,PPIA,gag |
| HIV Infection | NMT1,AP1B1,DOCK2,APOBEC3G,ELL,PSIP1,PACS1,PPIAL4A,PSTPIP2,CDK9 |
| Infectious disease | LTF,RCC1,AP1S1,STX1B,NMT1,DOCK2,AP1M2,AP1G1,PACS1,SYT2 |
Protein Function
NMT2 has several biochemical functions, for example, glycylpeptide N-tetradecanoyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NMT2 itself. We selected most functions NMT2 had, and list some proteins which have the same functions with NMT2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glycylpeptide N-tetradecanoyltransferase activity | NMT1,NMT1B,NMT1A |
Interacting Protein
NMT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NMT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NMT2.
TP53;BCL2;CASP3;TK1;ANXA4;ANXA7;CSNK2B;PRKCZ;SMN1;TMED9
Resources
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References
- Nasr, R; Johns, C; et al. Collapsing glomerulopathy in collagen vascular-like disease. LUPUS 23:75-80(2014).
- Yu, C; Xu, L; et al. PRBC-derived plasma induces non-muscle myosin type IIA-mediated neutrophil migration and morphologic change. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 35:71-79(2013).
Reviews
The activity of Human NMT2 protein produced by Creative-Biomart is good. Fortunately, it is working well now.
