NLGN2

  • Official Full Name

    neuroligin 2
  • Synonyms

    NLGN2;neuroligin 2;neuroligin-2;KIAA1366

Recombinant Proteins

  • Human
  • Mouse
  • Rhesus macaque
  • Rat
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • His&GST
  • His&Fc&Avi

    Involved Pathway

    NLGN2 involved in several pathways and played different roles in them. We selected most pathways NLGN2 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with NLGN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell adhesion molecules (CAMs) HLA-DRB1,CLDN7B,VCAN,HLA-DQA1,CLDNE,ITGB8,CLDNC,HLA-DOB,F11R.1,PDCD1

    Protein Function

    NLGN2 has several biochemical functions, for example, cell adhesion molecule binding,NOT cholinesterase activity,neurexin family protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NLGN2 itself. We selected most functions NLGN2 had, and list some proteins which have the same functions with NLGN2. You can find most of the proteins on our site.

    Function Related Protein
    neurexin family protein binding NLGN4Y,SDCBP,SYTL4,NLGN4A,SYTL1,NLGN2A,NLGN3B,SYTL3,NLGN1,NLGN3
    NOT cholinesterase activity NLGN4B,NLGN1,NLGN2B,NLGN3A,NLGN4A,NLGN4Y,NLGN3,NLGN3B,NLGN4X,NLGN2A
    receptor activity SMAGP,CCR6,CMKLR1,XPR1,CD7,NLGN1,CADM1B,MED14,ICAM1,VMN1R40
    cell adhesion molecule binding CXADR,SMAGP,CADM2A,CPE,POSTNB,NLGN4X,PVRL2L,NCR3,DSG2,ITGB2

    Interacting Protein

    NLGN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NLGN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NLGN2.

    Resources

    References

    • Hill-Yardin, EL; Argyropoulos, A; et al. Reduced susceptibility to induced seizures in the Neuroligin-3(R451C) mouse model of autism. NEUROSCIENCE LETTERS 589:57-61(2015).
    • Zhang, Y; Dixon, CL; et al. Functional reconstitution of glycinergic synapses incorporating defined glycine receptor subunit combinations. NEUROPHARMACOLOGY 89:391-397(2015).

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