NLGN1
-
Official Full Name
neuroligin 1 -
Overview
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. -
Synonyms
NLGN1;neuroligin 1;neuroligin-1;KIAA1070;NLG 1;MGC45115;NLG1;OTTHUMP00000211275;OTTHUMP00000211276;NL1
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Rat
- Zebrafish
- Mouse
- Mammalian Cells
- HEK293
- Human Cells
- E.coli
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- Flag
- His&Fc&Avi
- GST
Involved Pathway
NLGN1 involved in several pathways and played different roles in them. We selected most pathways NLGN1 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with NLGN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell adhesion molecules (CAMs) | HLA-DOB,CLDN3,CD8B1,CDH3,MAG,CLDNB,PVRL3B,PDCD1LG2,OCLNB,HLA-G |
Protein Function
NLGN1 has several biochemical functions, for example, PDZ domain binding,cell adhesion molecule binding,NOT cholinesterase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NLGN1 itself. We selected most functions NLGN1 had, and list some proteins which have the same functions with NLGN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NOT cholinesterase activity | NLGN4B,NLGN2A,NLGN2B,NLGN4Y,NLGN3,NLGN3A,NLGN4A,NLGN4X,NLGN3B,NLGN2 |
| PDZ domain binding | LRP2,ATP2B1A,SRR,FZD1,ATP2B4,PLEKHA2,LIN7B,GRM7,LPAR1,GRID2 |
| scaffold protein binding | NLGN3,SRC,KCNQ1,VIM,SHANK1,TREM1,GRIN2A,ADCY6,P2RY1,CIT |
| receptor activity | PAQR3B,VMN1R50,XPR1,TNFRSF11B,GFRA1B,ANTXR2,ITGAX,MED30,TRAM1,ANTXR2A |
| cell adhesion molecule binding | ITGAL,PVRL3,NLGN4Y,SMAGP,NRXN1,DSG2,TIGIT,NLGN3,VCAM1,NCR3 |
| neurexin family protein binding | NLGN3,SDCBP,LRRTM2,NLGN4X,SYTL2,SYTL4,NLGN4A,NLGN2B,CPE,SYTL3 |
| protein dimerization activity | ARNTL2,HPS4,AHR2,HIF1AB,PEX3,SCXA,SMG1,EBF4,HER1,MEF2CB |
Interacting Protein
NLGN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NLGN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NLGN1.
DLG4;Dlg3;ABI2;CD247;BRK1
Resources
Related Services
Related Products
References
