NKX2-3
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Official Full Name
NK2 transcription factor related, locus 3 (Drosophila) -
Overview
This gene encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiat -
Synonyms
NKX2-3;NK2 transcription factor related, locus 3 (Drosophila);homeobox protein Nkx-2.3;Homeobox protein NK-2 homolog C;homeobox protein NKX2-3 homolog;MGC127415;NK-2 (Drosophila) homolog C;NK2 transcription factor homolog C;NK2 transcription factor related, locus 3;NK2.3;NKX2.3;NKX23;NKX2C;tinman;nkx2-C;homeobox protein NK-2 homolog 3;Drosophila NK2 transcription factor related, locus 3;Nkx-2.3
Recombinant Proteins
- Mouse
- Chicken
- Human
- Mammalian Cell
- E.coli
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NKX2-3-10699M | Recombinant Mouse NKX2-3 Protein | Mammalian Cell | Mouse | His |
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| NKX2-3-6588C | Recombinant Chicken NKX2-3 | Mammalian Cell | Chicken | His |
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| NKX2-3-301372H | Recombinant Human NKX2-3 protein, GST-tagged | E.coli | Human | GST | Asn19-Arg148 |
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| NKX2-3-5898H | Recombinant Human NKX2-3 Protein, GST-tagged | Wheat Germ | Human | GST | 1-293 a.a. |
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| NKX2-3-6084M | Recombinant Mouse NKX2-3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NKX2-3-6084M-B | Recombinant Mouse NKX2-3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| NKX2-3-6678HF | Recombinant Full Length Human NKX2-3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 293 amino acids |
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Involved Pathway
NKX2-3 involved in several pathways and played different roles in them. We selected most pathways NKX2-3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NKX2-3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
NKX2-3 has several biochemical functions, for example, DNA binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKX2-3 itself. We selected most functions NKX2-3 had, and list some proteins which have the same functions with NKX2-3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | TCF7,HMX4,DLX3B,POU5F3,RBPJ,FOXD1,HOXC10A,ZNF192,ERG,PAX3 |
| DNA binding | AHR1A,LZTS1,RNF6,NR1D1,ZIC5,AHCTF1,GM14482,DMBX1B,HOXB8A,ABL1 |
Interacting Protein
NKX2-3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKX2-3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NKX2-3.
Resources
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References
- Plevy, S; Silverberg, MS; et al. Combined Serological, Genetic, and Inflammatory Markers Differentiate Non-IBD, Crohn's Disease, and Ulcerative Colitis Patients. INFLAMMATORY BOWEL DISEASES 19:1139-1148(2013).
- Kellermayer, Z; Labadi, A; et al. Absence of Nkx2-3 Homeodomain Transcription Factor Induces the Formation of LYVE-1-Positive Endothelial Cysts without Lymphatic Commitment in the Spleen. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 59:690-700(2011).
